SCHEMBL534357

SCHEMBL534357

C=CC(=O)OC(F)CC(F)(F)C(F)(F)CCC(F)(F)C(F)(F)CCC(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL535074 1.00 TSHR (0.31) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL4446616 0.89
SCHEMBL4446249 0.89
SCHEMBL6847445 0.81 TSHR (0.32) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL42235 0.80 TSHR (0.35) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL8601132 0.80 TSHR (0.31) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL449783 0.80 TSHR (0.31) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL3125065 0.80 TSHR (0.31) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL534647 0.75 TSHR (0.33) TSHRALDH1A1
SCHEMBL534392 0.75 TSHR (0.33) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2276781-B1 ETHYLENE-TETRAFLUOROETHYLENE INTERMEDIATES DU PONT (US) 2012-11-07 EP claimed
US-8212064-B2 Ethylene tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-03 US claimed
US-20090287010-A1 Ethylene-tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-19 US claimed
US-8318877-B2 Ethylene tetrafluoroethylene (meth)acrylate copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-11-27 US disclosed
US-8314037-B2 Fluoropolymer emulsions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-11-20 US disclosed
EP-2276781-B1 ETHYLENE-TETRAFLUOROETHYLENE INTERMEDIATES DU PONT (US) 2012-11-07 EP disclosed
US-8212064-B2 Ethylene tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-03 US disclosed
EP-2217630-B1 FLUOROPOLYMER EMULSIONS DU PONT (US) 2012-02-29 EP disclosed
EP-2283051-B1 ETHYLENE TETRAFLUOROETHYLENE (METH)ACRYLATE COPOLYMERS DU PONT (US) 2012-02-08 EP disclosed
EP-2283051-A1 ETHYLENE TETRAFLUOROETHYLENE (METH)ACRYLATE COPOLYMERS E. I. du Pont de Nemours and Company (US) 2011-02-16 EP disclosed
WO-2009143194-A1 ETHYLENE TETRAFLUOROETHYLENE (METH)ACRYLATE COPOLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-26 WO disclosed
US-20090291222-A1 Ethylene tetrafluoroethylene (meth)acrylate copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-26 US disclosed
US-20090287010-A1 Ethylene-tetrafluoroethylene intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-19 US disclosed
US-20090149096-A1 FLUOROPOLYMER EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 US disclosed
US-20090148653-A1 FLUOROPOLYMER EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 US disclosed