Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601132 | 1.00 | TSHR (0.31) | TSHRTHRBALDH1A1TP53CYP3A4 | |
| SCHEMBL3125065 | 1.00 | TSHR (0.31) | TSHRTHRBALDH1A1TP53CYP3A4 | |
| SCHEMBL6847445 | 0.98 | TSHR (0.32) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL4446249 | 0.89 | — | — | |
| SCHEMBL4446616 | 0.89 | — | — | |
| SCHEMBL11401308 | 0.87 | TSHR (0.33) | TSHR | |
| SCHEMBL1532964 | 0.87 | TSHR (0.38) | TSHR | |
| SCHEMBL11862823 | 0.86 | THRB (0.32) | THRB | |
| SCHEMBL18317983 | 0.84 | ALDH1A1 (0.30) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL20538783 | 0.84 | ALDH1A1 (0.31) | TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11045833-B2 | Task specific ionic liquid-impregnated polymeric surface coatings for antibacterial, antifouling, and metal scavenging activity | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-29 | — | — | US | claimed |
| EP-3308613-B1 | METHOD FOR FORMING A COATING ON AN ELECTRONIC OR ELECTRICAL DEVICE | P2I LTD (GB) | 2020-08-05 | — | — | EP | claimed |
| EP-3583211-B1 | METHOD FOR THE SYNTHESIS OF DNA CONJUGATES BY MICELLAR CATALYSIS | UNIV DORTMUND TECH (DE) | 2024-04-10 | — | — | EP | disclosed |
| EP-4350031-A1 | PLASMA POLYMERISATION COATING, PREPARATION METHOD, AND DEVICE | Jiangsu Favored Nanotechnology Co., Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |
| US-11725071-B2 | Copolymers of halogenated olefins and halogenated co-monomers | ARKEMA INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-11407993-B2 | Method for the synthesis of DNA conjugates by micellar catalysis | TECHNISCHE UNIVERSITAET DORTMUND (DE) | 2022-08-09 | — | — | US | disclosed |
| US-20220002712-A1 | METHOD FOR THE SYNTHESIS OF DNA CONJUGATES BY MICELLAR CATALYSIS | TECHNISCHE UNIVERSITÄT DORTMUND (DE) | 2022-01-06 | — | — | US | disclosed |
| US-20200299433-A1 | COPOLYMERS OF HALOGENATED OLEFINS AND HALOGENATED CO-MONOMERS | ARKEMA INC. | 2020-09-24 | — | — | US | disclosed |
| US-10755942-B2 | Method of forming topcoat for patterning | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-08-25 | — | — | US | disclosed |
| US-10010502-B2 | Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation | AMORPHEX THERAPEUTICS LLC (US) | 2018-07-03 | — | — | US | disclosed |
| US-20180122648-A1 | Method of Forming Topcoat for Patterning | NATIONAL SCIENCE FOUNDATION | 2018-05-03 | — | — | US | disclosed |
| US-5194556-A | Macromolecular monomer derived from polysiloxane copolymerized with fluoroacrylate | CIBA-GEIGY CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| WO-1993004132-A1 | LOW LOSS HIGH NUMERICAL APERTURE CLADDED OPTICAL FIBERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| EP-0494842-A2 | Rigid contact lenses with improved oxygen permeability | CIBA-GEIGY AG (CH) | 1992-07-15 | — | — | EP | disclosed |
| EP-0493320-A2 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |
| US-5115056-A | FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| US-5079319-A | Contact Lenses | CIBA-GEIGY CORPORATION (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0425436-A2 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA-GEIGY AG (CH) | 1991-05-02 | — | — | EP | disclosed |
| US-5010141-A | Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0406161-A2 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010502-B2 | Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation | MYOC, STRA6, MYOF | TSHR 1045/4885THRB 2774/4885ALDH1A1 1432/4885 |
| US-11045833-B2 | Task specific ionic liquid-impregnated polymeric surface coatings for antibacterial, antifouling, and metal scavenging activity | LPO, SOD1, ICMT | TSHR 2751/4885THRB 3669/4885ALDH1A1 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.