SCHEMBL42235

SCHEMBL42235

C=CC(=O)OC(F)CC(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.35
ALDH1A1 P00352 4/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.33
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9243028 0.83 HCAR2 (0.34)
SCHEMBL6847445 0.82 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8601132 0.80 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL534357 0.80 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL449783 0.80 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL535074 0.80 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3125065 0.80 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29740079 0.79 ALDH1A1 (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8373742 0.78 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1532964 0.78 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 811 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852521-B Fluorine-containing resin for manufacturing pixel Bank layer, synthesis process of fluorine-containing resin and fluorine-containing resin composition 江苏博砚电子科技股份有限公司 2025-06-24 CN claimed
CN-119081011-A Preparation method for converting biomass into fluorine-containing thermoplastic elastomer 广东工业大学 2024-12-06 CN claimed
CN-118852521-A Fluorine-containing resin for manufacturing pixel Bank layer, synthesis process of fluorine-containing resin and fluorine-containing resin composition 江苏博砚电子科技股份有限公司 2024-10-29 CN claimed
CN-118841532-A Silicon-carbon composite material, preparation method and application thereof 碳一新能源集团有限责任公司 2024-10-25 CN claimed
CN-118562503-A Composite material and preparation method thereof 清华大学 2024-08-30 CN claimed
CN-117913346-B Composite solid electrolyte and preparation method and application thereof 浙江大学 2024-08-16 CN claimed
CN-118325037-A Stain-resistant ultraviolet light-moisture mixed cured resin and preparation method thereof 深圳职业技术大学 2024-07-12 CN claimed
CN-118240139-A Alkali-soluble resin, photoresist composition and application thereof 固安鼎材科技有限公司 2024-06-25 CN claimed
CN-115463372-B Fluorine-containing extinguishing agent microsphere and preparation method thereof 杭州应星新材料有限公司 2024-06-07 CN claimed
CN-117986438-A Super-wetting fluorine-containing acrylate applied to anti-fouling paint and preparation method thereof 安徽徽邦漆业有限公司 2024-05-07 CN claimed
US-20010053822-A1 Dispersion-controlled polymers for broad band fiber optic devices CHAN KWOK P (US) 2001-12-20 US claimed
EP-1125962-A2 Novel poly(siloxane-acrylate) elastomers with oxycarbonylethyleneimino-containing organic groups and method of making the same DOW CORNING CORPORATION (US) 2001-08-22 EP claimed
US-6268435-B1 OPTICAL FIBERS FOR PROPAGATION OF OPTICAL ENERGY, INFRARED ABSORBING DYE AND POLAR OLEFIN COPOLYMER MOLECULAR OPTOELECTRONICS CORPORATION 2001-07-31 US claimed
US-6265514-B1 USING BASE EQUILIBRIUM CATALYST DOW CORNING CORPORATION 2001-07-24 US claimed
US-6248805-B1 THERMAL INK JET PRNTING HEWLETT-PACKARD COMPANY 2001-06-19 US claimed
US-6205280-B1 Blockless fiber optic attenuators and attenuation systems employing dispersion controlled polymers MOLECULAR OPTOELECTRONICS CORPORATION 2001-03-20 US claimed
US-6191224-B1 CONTROLLED OPTICAL DISPERSION MOLECULAR OPTOELECTRONICS CORPORATION 2001-02-20 US claimed
US-6057384-A VEHICLE AND COLORANT ASSOCIATED WITH A PRIMER CORE/SHELL POLYMER; DURABLR SMEAR-FAST FILM HEWLETT-PACKARD COMPANY (US) 2000-05-02 US claimed
US-5990202-A DURABLE, SMEAR-FAST INK FILMS COMPRISING DUAL ENCAPSULATED COLORANT; A PRIMER CORE/SHELL POLYMER COATING A COLORANT (ADHESION) AND AN EXTERIOR CORE/SHELL POLYMER COATING FOR DURABILITY HEWLETT-PACKARD COMPANY (US) 1999-11-23 US claimed
US-4387203-A COPOLYMER OF AN UNSATURATED NITRILE, CONJUGATED DIENE AND UNSATURATED FLUORINE COMPOUND GASOLINE RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-06-07 US claimed