Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.39 |
| ▸ | PTPRB | P23467 | 5/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534415 | 0.82 | CTSS (0.36) | CTSSCTSKCYP3A4PTPRBKMT2A | |
| SCHEMBL533795 | 0.81 | SLC1A3 (0.35) | CTSSPTPRBSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3459165 | 0.81 | PTGER2 (0.38) | SLC1A3SLC1A2SLC1A1KMT2AADAM17 | |
| SCHEMBL534416 | 0.80 | PTGER2 (0.57) | PTGER2 | |
| SCHEMBL6519267 | 0.79 | PTGER2 (0.34) | CTSSSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL6519253 | 0.77 | SLC1A3 (0.34) | CTSSSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL534320 | 0.73 | PTGER2 (0.38) | PTPRBSLC1A3SLC1A2SLC1A1BCL2 | |
| SCHEMBL12982541 | 0.73 | PTGER2 (0.53) | PTGER2 | |
| SCHEMBL533647 | 0.73 | PTGER2 (0.41) | PTPRBBCL2PTGER2 | |
| SCHEMBL10322183 | 0.73 | PTPRB (0.35) | PTPRBSLC1A3SLC1A2SLC1A1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415763-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | Ube Industries, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |