Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534417 | 0.82 | CTSS (0.40) | CTSSCTSKCYP3A4PTGER2KMT2A | |
| SCHEMBL533797 | 0.81 | PTGER2 (0.36) | PTGER2KMT2AMMP1MMP9MMP13 | |
| SCHEMBL534416 | 0.81 | PTGER2 (0.57) | PTGER2 | |
| SCHEMBL533799 | 0.79 | PTGER2 (0.34) | PTGER2KMT2AMMP1MMP9MMP13 | |
| SCHEMBL533798 | 0.78 | PTGER2 (0.33) | PTGER2KMT2AMMP1MMP9MMP13 | |
| SCHEMBL3459175 | 0.77 | PTGER2 (0.40) | PTGER2KMT2AMMP1MMP9MMP13 | |
| SCHEMBL3459169 | 0.77 | PTGER2 (0.41) | PTGER2 | |
| SCHEMBL3459172 | 0.76 | PTGER2 (0.36) | PTGER2KMT2AMMP1MMP9MMP13 | |
| SCHEMBL534322 | 0.73 | PTGER2 (0.41) | PTGER2 | |
| SCHEMBL10322180 | 0.71 | PTGER2 (0.34) | PTGER2MMP1MMP9MMP13PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415763-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | Ube Industries, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |