Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A2 | O00482 | 1/20 | 0.58 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.42 |
| ▸ | GLRB | P48167 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5346040 | 0.84 | NR5A2 (0.64) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5335689 | 0.83 | NR5A2 (0.63) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12477516 | 0.82 | NR5A2 (0.54) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12477683 | 0.82 | NR5A2 (0.54) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29670054 | 0.82 | NR5A2 (0.56) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30861606 | 0.82 | NR5A2 (0.56) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28742131 | 0.82 | NR5A2 (0.56) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27195660 | 0.82 | NR5A2 (0.56) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28378284 | 0.81 | LMNA (0.45) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28755857 | 0.81 | LMNA (0.41) | NR5A2NR5A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471264-B | 5, 5-disubstituted-2-imino pyrrolidine derivative, preparation method and medical application thereof | SHANGHAI HENGRUI PHARM CO LTD | 2014-04-02 | — | — | CN | disclosed |
| CN-102471264-A | 5, 5-disubstituted-2-imino pyrrolidine derivative, preparation method and medical application thereof | SHANGHAI HENGRUI PHARM CO LTD | 2012-05-23 | — | — | CN | disclosed |
| US-7157398-B2 | Covalently fixed nonmetallocenes, process for preparing them and their use for the polymerization of olefins | CELANESE VENTURES GMBH (DE) | 2007-01-02 | — | — | US | disclosed |
| US-20050148461-A1 | Covalently fixed nonmetallocenes, process for preparing them and their use for the polymerization of olefins | CELANESE VENTURES GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| US-6872843-B2 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-03-29 | — | — | US | disclosed |
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | EQUISTAR CHEMICALS, LP | 2004-02-05 | — | — | US | disclosed |
| CN-88100518-A | 3-phenyl-7H-the thiazole that replaces also [3,2-b] [1,2,4] triazine-7-ketone, the method for preparing them contains their medicament and application and some intermediate of relating in such compound | — | 1988-08-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | SOAT2, NOTUM, SOAT1 | NR5A2 3574/4885NR5A1 1517/4885CYP1A2 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.