Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27994848 | 0.79 | POLB (0.43) | POLBCYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL3869151 | 0.75 | MAPK1 (0.44) | POLBCYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL201873 | 0.73 | MAPT (0.40) | POLBCYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL3861252 | 0.73 | PIN1 (0.38) | PIN1MAPT | |
| SCHEMBL3862001 | 0.71 | PTGES (0.42) | SMN1; SMN2PIN1MAPT | |
| SCHEMBL202880 | 0.70 | POLB (0.51) | POLBCYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL4727431 | 0.70 | POLB (0.51) | POLBCYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL15923536 | 0.70 | CYP1A2 (0.45) | POLBCYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL4157332 | 0.70 | PDE10A (0.40) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1043132 | 0.70 | MEN1 (0.41) | POLBCYP1A2TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106852-A2 | SUBSTITUTED FUSED[1,2]IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-09-20 | — | — | WO | disclosed |