Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878417 | 0.84 | AKR1C3 (0.54) | AKR1C3AKR1C2MMP9CYP2D6SLC6A2 | |
| SCHEMBL15341770 | 0.84 | AKR1C3 (0.54) | AKR1C3AKR1C2MMP9CYP2D6SLC6A2 | |
| SCHEMBL6378903 | 0.77 | MMP8 (0.50) | AKR1C3AKR1C2MMP9CYP2D6SLC6A2 | |
| SCHEMBL15161021 | 0.77 | TSHR (0.58) | LMNAAKR1C3AKR1C2CYP1A2TSHR | |
| SCHEMBL15160899 | 0.75 | PTGS2 (0.54) | LMNAAKR1C3AKR1C2CYP1A2TSHR | |
| SCHEMBL17488483 | 0.75 | PTGS2 (0.54) | LMNAAKR1C3AKR1C2CYP1A2TSHR | |
| SCHEMBL15160897 | 0.75 | PTGS2 (0.53) | AKR1C3AKR1C2CYP1A2TSHR | |
| SCHEMBL15161062 | 0.75 | PTGS2 (0.53) | AKR1C3AKR1C2CYP1A2TSHR | |
| SCHEMBL27734602 | 0.75 | AKR1C3 (0.52) | AKR1C3AKR1C2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5860496 | 0.75 | CYP2D6 (0.50) | AKR1C3AKR1C2MMP9CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238775-B2 | Receptor(SSTR4)-selective somatostatin analogs | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2007-07-03 | — | — | US | disclosed |
| US-20050245438-A1 | Receptor(SSTR4)-selective somatostatin analogs | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2005-11-03 | — | — | US | disclosed |
| WO-2004009614-A2 | RECEPTOR (SSTR4)- SELECTIVE SOMATOSTATIN ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2004-01-29 | — | — | WO | disclosed |