Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336103 | 0.80 | SIGMAR1 (0.39) | SLC6A4SLC6A2SLC6A3HTR2CKCNH2 | |
| SCHEMBL6689767 | 0.80 | SIGMAR1 (0.39) | SLC6A4SLC6A2SLC6A3HTR2CKCNH2 | |
| SCHEMBL25945067 | 0.73 | SLC6A4 (0.51) | OXTRAVPR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL25807458 | 0.69 | SLC6A4 (0.47) | OXTRAVPR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14047771 | 0.66 | HTR2C (0.53) | SLC6A4SLC6A2SLC6A3HTR2CSCD | |
| SCHEMBL10261369 | 0.66 | HTR2C (0.53) | SLC6A4SLC6A2SLC6A3HTR2CSCD | |
| SCHEMBL10274504 | 0.65 | SCD (0.56) | SLC6A4SLC6A2SLC6A3HTR2CKCNH2 | |
| SCHEMBL9450757 | 0.64 | SLC6A4 (0.45) | OXTRAVPR1ASLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL5332083 | 0.64 | SLC6A2 (0.41) | GRIN1GRIN2BSLC6A2SLC6A3CYP2D6 | |
| SCHEMBL2637086 | 0.64 | RBP4 (0.48) | GRIN1GRIN2BSLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288537-B2 | Azetidine derivatives as CCR-3 receptor antagonists | NOVARTIS AG (CH) | 2007-10-30 | — | — | US | disclosed |
| US-20050222118-A1 | Azetidine derivatives as ccr-3 receptor antagonists | NOVARTIS AG (CH) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222118-A1 | Azetidine derivatives as ccr-3 receptor antagonists | CCR3, CCR1, CCR9 | GRIN1 484/4885GRIN2B 704/4885OXTR 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.