SCHEMBL5347101

SCHEMBL5347101

CCOC(=O)NC(=O)C1CC2C=CC1C2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
TRPM8 Q7Z2W7 1/20 0.47
ALDH1A1 P00352 7/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
THRB P10828 1/20 0.40
HPGD P15428 1/20 0.39
NFKB1 P19838 2/20 0.39
NFKB2 Q00653 2/20 0.39
RELA Q04206 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 2/20 0.39
RAB9A P51151 3/20 0.38
APEX1 P27695 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
ESR2 Q92731 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5360459 0.84 KDM4E (0.61) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL2754655 0.79 ALDH1A1 (0.49) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL11702317 0.79 ALDH1A1 (0.49) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL31178091 0.79 ALDH1A1 (0.49) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL2754654 0.79 ALDH1A1 (0.49) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL29452889 0.79 ALDH1A1 (0.49) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL200507 0.79 ALDH1A1 (0.49) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL5360021 0.78 KDM4E (0.57) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL10407216 0.77 ALDH1A1 (0.51) KDM4ELMNAALDH1A1HPGDKMT2A
SCHEMBL8852547 0.77 KDM4E (0.47) KDM4ELMNAALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7202016-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2007-04-10 US disclosed
US-20050214680-A1 Radiation-sensitive resin composition MIYAJI MASAAKI 2005-09-29 US disclosed
US-6933094-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-08-23 US disclosed
US-20020058201-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-05-16 US disclosed
EP-1193558-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-04-03 EP disclosed