Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320666 | 0.78 | MAPK14 (0.43) | GRM5AKT1AKT2 | |
| SCHEMBL5342580 | 0.78 | TDP1 (0.47) | KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5340690 | 0.75 | MAOB (0.40) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5320129 | 0.73 | AKT1 (0.46) | GRM5KDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL5335624 | 0.73 | KDM4E (0.38) | GRM5KDM4ERAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5319501 | 0.72 | KDM4E (0.37) | GRM5KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5354165 | 0.69 | AKT1 (0.44) | GRM5AKT1AKT2 | |
| SCHEMBL5341386 | 0.69 | AKT1 (0.49) | GRM5KDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5321323 | 0.68 | AKT1 (0.50) | GRM5KDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL5324372 | 0.67 | AKT1 (0.55) | GRM5KDM4ERAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |