Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | AOC2 | O75106 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207361 | 0.81 | TSHR (0.42) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL12301112 | 0.81 | TSHR (0.42) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL96749 | 0.78 | TSHR (0.44) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL194092 | 0.78 | TSHR (0.43) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13665348 | 0.78 | TSHR (0.43) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL536189 | 0.75 | CA1 (0.65) | TSHRSMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL12853863 | 0.75 | KMT2A (0.41) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL5535600 | 0.75 | SCN4A (0.42) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9317193 | 0.75 | TSHR (0.41) | TSHRMEN1NPC1RAB9AKMT2A | |
| Methyl Alcohol SCHEMBL4209931 | 0.75 | TSHR (0.41) | TSHRMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021014671-A1 | RESIN COMPOSITION FOR TEMPERATURE SENSOR, AND ELEMENT FOR TEMPERATURE SENSOR | 株式会社クレハ | 2021-01-28 | — | — | WO | claimed |
| US-8063093-B2 | Derivatives of 5-(halo)alkanoyl-6-hydroxy- benozofuran, benzothiophene, or indole; autoimmune diseases; systemic lupus erythematosis, rheumatoid arthritis, multiple sclerosis and psoriasis, transplant rejection; antiproliferative, anticarcinogenic, antidiabetic, antiinflammatory and antiulcer agents | HARVEY ANDREW J (AU) | 2011-11-22 | — | — | US | claimed |
| US-20080221194-A1 | Novel Potassium channel Blockers and Uses Thereof | HARVEY ANDREW J | 2008-09-11 | — | — | US | claimed |
| EP-1805143-A1 | PYRIDINE DERIVATIVES AND THE PREPARATION AND THE THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2007-07-11 | — | — | EP | claimed |
| WO-2006096911-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | HARVEY ANDREW J (AU) | 2006-09-21 | — | — | WO | claimed |
| WO-2006042955-A1 | PYRIDINE DERIVATIVES AND THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2006-04-27 | — | — | WO | claimed |
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |
| EP-0543919-A1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS FOR TREATMENT OF CNS DISEASES. | SEARLE & CO (US) | 1993-06-02 | — | — | EP | claimed |
| WO-1992003131-A1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS FOR TREATMENT OF CNS DISEASES | G.D. SEARLE & CO. (US) | 1992-03-05 | — | — | WO | claimed |
| WO-1987002983-A1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-21 | — | — | WO | claimed |
| US-12031002-B2 | Prepreg, method for producing prepreg, and molded article | DIC CORPORATION (JP) | 2024-07-09 | — | — | US | disclosed |
| EP-4364950-A1 | ACTINIC RAY-CURABLE INKJET INK COMPOSITION | Sakata INX Corporation (JP) | 2024-05-08 | — | — | EP | disclosed |
| WO-2024089979-A1 | POWDER DEPOSITION PRINTING METHOD | サカタインクス株式会社 | 2024-05-02 | — | — | WO | disclosed |
| EP-4357097-A1 | SELF-ASSEMBLED CARBON FIBER BUNDLES, METHOD FOR PRODUCING SAME, PREPREG AND METHOD FOR PRODUCING SAME | Mitsubishi Chemical Corporation (JP) | 2024-04-24 | — | — | EP | disclosed |
| US-11958920-B2 | Active energy ray curable composition | ASIA STENCIL PAPER CO., LTD. (JP) | 2024-04-16 | — | — | US | disclosed |
| US-4374841-A | HYPOTENSIVE, ADRENERGIC BLOCKING, AND CARDIOTONIC AGENTS; CENTRAL DEPRESSANTS | S. A. LABAZ N.V. (BE) | 1983-02-22 | — | — | US | disclosed |
| US-RE29577-E | Anthraquinone dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |
| US-4045416-A | PROTECTIVE COATINGS | UNION CARBIDE CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3963763-A | Anthraquinone dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-15 | — | — | US | disclosed |
| US-3963771-A | PROTECTIVE COATINGS | UNION CARBIDE CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221194-A1 | Novel Potassium channel Blockers and Uses Thereof | KCNAB1, KCNB1, KCNMB1 | TSHR 2890/4885MEN1 1284/4885NPC1 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.