Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1492486 | 0.87 | MCHR1 (0.33) | TDP1SERPINE1MCHR1CNR2NPC1 | |
| SCHEMBL115913 | 0.83 | MCHR1 (0.35) | TDP1SERPINE1KMT2AMCHR1CNR2 | |
| SCHEMBL3766082 | 0.82 | TDP1 (0.33) | TDP1SERPINE1KMT2APTGESALOX5 | |
| SCHEMBL3766085 | 0.80 | BID (0.33) | TDP1SERPINE1MCHR1KCNH2 | |
| SCHEMBL534940 | 0.75 | LIPG (0.43) | TDP1RECQLKCNH2 | |
| SCHEMBL3766087 | 0.72 | RECQL (0.36) | TDP1KMT2ACNR2RECQLCA12 | |
| SCHEMBL29028581 | 0.72 | TDP1 (0.60) | TDP1SERPINE1PTGESALOX5MCHR1 | |
| SCHEMBL29028661 | 0.68 | MCHR1 (0.59) | TDP1SERPINE1KMT2APTGESALOX5 | |
| SCHEMBL5573340 | 0.68 | LIPG (0.39) | TDP1ALOX5TSHR | |
| SCHEMBL28206790 | 0.67 | MYC (0.36) | TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414108-A2 | METHOD FOR MODIFYING THE SURFACE ENERGY OF A SOLID | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112610-A2 | METHOD FOR MODIFYING THE SURFACE ENERGY OF A SOLID | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2010-10-07 | — | — | WO | disclosed |