SCHEMBL534940

SCHEMBL534940

CCCCCCCCCCCCCc1ccccc1S(=O)(=O)N(F)CCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.43
KCNH2 Q12809 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
CYSLTR2 Q9NS75 3/20 0.39
CYSLTR1 Q9Y271 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
BID P55957 3/20 0.38
MCL1 Q07820 3/20 0.38
BCL2L1 Q07817 2/20 0.38
BAK1 Q16611 2/20 0.38
KAT8 Q9H7Z6 2/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
EP300 Q09472 1/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
KAT5 Q92993 1/20 0.38
SAE1 Q9UBE0 1/20 0.38
THRA P10827 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18095808 0.79 LIPG (0.45) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL8520962 0.78 LIPG (0.53) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL29028581 0.77 TDP1 (0.60) KCNH2TDP1
SCHEMBL8213690 0.77 LIPG (0.53) LIPGKCNH2NR1H2NR1H3CYSLTR2
SCHEMBL10930852 0.77 KCNH2 (0.47) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL28303872 0.77 LIPG (0.51) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL1714372 0.77 LIPG (0.51) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL1948496 0.76 LIPG (0.51) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL578729 0.75 LIPG (0.50) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL1403975 0.75 LIPG (0.50) LIPGNR1H2NR1H3CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414108-B1 METHOD FOR MODIFYING THE SURFACE ENERGY OF A SOLID COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-09-27 EP disclosed
EP-2414108-A2 METHOD FOR MODIFYING THE SURFACE ENERGY OF A SOLID Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2012-02-08 EP disclosed
WO-2010112610-A2 METHOD FOR MODIFYING THE SURFACE ENERGY OF A SOLID Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2010-10-07 WO disclosed