Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | PPM1A | P35813 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349782 | 1.00 | F2RL3 (0.42) | F2RL3KCNK3PPM1ASCN5ASCN9A | |
| SCHEMBL5336983 | 0.94 | F2RL3 (0.43) | F2RL3KCNK3PPM1ASCN5ASCN9A | |
| SCHEMBL5336985 | 0.94 | F2RL3 (0.43) | F2RL3KCNK3PPM1ASCN5ASCN9A | |
| SCHEMBL5337868 | 0.91 | ENPP2 (0.38) | F2RL3KCNK3SCN5ASCN9ARORC | |
| SCHEMBL5333741 | 0.91 | F2RL3 (0.37) | F2RL3PPM1ASCN5ASCN9AENPP2 | |
| SCHEMBL5333744 | 0.91 | F2RL3 (0.37) | F2RL3PPM1ASCN5ASCN9AENPP2 | |
| SCHEMBL5337864 | 0.91 | ENPP2 (0.38) | F2RL3KCNK3SCN5ASCN9ARORC | |
| SCHEMBL5321176 | 0.91 | F2RL3 (0.45) | F2RL3KCNK3PPM1ARORCENPP2 | |
| SCHEMBL5321178 | 0.91 | F2RL3 (0.45) | F2RL3KCNK3PPM1ARORCENPP2 | |
| SCHEMBL5316760 | 0.86 | KCNK3 (0.37) | KCNK3ENPP2CYP2C19PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |