SCHEMBL5349864

SCHEMBL5349864

Cc1ccccc1C1(O)CCCCC1

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.54
OPRD1 P41143 2/20 0.54
OPRK1 P41145 2/20 0.54
OPRL1 P41146 2/20 0.54
HDAC4 P56524 1/20 0.51
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GRIN2B Q13224 4/20 0.41
PDE7A Q13946 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
P2RX7 Q99572 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28994161 0.94 OPRM1 (0.56) OPRM1OPRD1OPRK1OPRL1HDAC4
SCHEMBL29060516 0.89 OPRM1 (0.59) OPRM1OPRD1OPRK1OPRL1HDAC4
SCHEMBL29484741 0.80 MEN1 (0.41) HDAC4ALDH1A1MAPTSMN1; SMN2SIGMAR1
SCHEMBL17733195 0.80 MEN1 (0.41) HDAC4ALDH1A1MAPTSMN1; SMN2SIGMAR1
SCHEMBL6058582 0.80 MEN1 (0.41) HDAC4ALDH1A1MAPTSMN1; SMN2SIGMAR1
SCHEMBL2270935 0.80 SIGMAR1 (0.62) OPRM1OPRD1OPRK1OPRL1HDAC4
SCHEMBL12862966 0.80 OPRM1 (0.51) OPRM1OPRD1OPRK1OPRL1HDAC4
SCHEMBL7101793 0.79 OPRM1 (0.37) OPRM1OPRD1OPRK1OPRL1SMN1; SMN2
SCHEMBL632646 0.79 OPRM1 (0.37) OPRM1OPRD1OPRK1OPRL1SMN1; SMN2
Hydrochloric Acid SCHEMBL8175707 0.79 SIGMAR1 (0.60) OPRM1OPRD1OPRK1OPRL1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10472446-B2 Composition, resin mold, photo imprinting method, method for manufacturing optical element, and method for manufacturing electronic element TOYO GOSEI CO., LTD. (JP) 2019-11-12 US disclosed
US-20160017074-A1 COMPOSITION, RESIN MOLD, PHOTO IMPRINTING METHOD, METHOD FOR MANUFACTURING OPTICAL ELEMENT, AND METHOD FOR MANUFACTURING ELECTRONIC ELEMENT TOYO GOSEI CO., LTD. (JP) 2016-01-21 US disclosed
US-8911543-B2 Phenylcyclohexanol derivatives as wax modifiers and gelators XEROX CORPORATION (US) 2014-12-16 US disclosed
US-20140165873-A1 Phenylcyclohexanol Derivatives As Wax Modifiers And Gelators XEROX CORPORATION (US) 2014-06-19 US disclosed
US-7273952-B2 Substituted C-cyclohexylmethylamine derivatives GRUENENTHAL GMBH (DE) 2007-09-25 US disclosed
US-7064236-B2 Substituted 1-aryl-but-3-enylamine and 1-aryl-but-2-enylamine compounds GRUNENTHAL GMBH (DE) 2006-06-20 US disclosed
US-7022739-B2 Substituted 1-aminobutan-3-ol compounds GRUENENTHAL GMBH (DE) 2006-04-04 US disclosed
US-4111917-A POLYURETHANES W. R. GRACE & CO. (US) 1978-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140165873-A1 Phenylcyclohexanol Derivatives As Wax Modifiers And Gelators NR1H3, RXRG, NR1H2 OPRM1 610/4885OPRD1 273/4885OPRK1 804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.