SCHEMBL5350137

SCHEMBL5350137

CCCCCCOc1ccc(-c2ncnc(-c3ccc(-c4ccccc4)cc3)n2)c(O)c1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 5/20 0.49
RARB P10826 3/20 0.47
PTPN1 P18031 1/20 0.45
NR5A1 Q13285 1/20 0.45
PDK2 Q15119 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
MAPK10 P53779 1/20 0.42
PLA2G4B P0C869 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH2 P05091 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29051494 0.98 PTPN11 (0.51) PTPN11RARBPTPN1NR5A1PDK2
SCHEMBL29693771 0.98 PTPN11 (0.51) PTPN11RARBPTPN1NR5A1PDK2
SCHEMBL27860728 0.96 PTPN11 (0.44) PTPN11RARBPTPN1LMNAGAA
SCHEMBL28144789 0.94 PTPN11 (0.46) PTPN11PTPN1LMNAGAAMAPK10
SCHEMBL27778872 0.92 LMNA (0.44) LMNAGAAMAPK10KDM4EALDH1A1
SCHEMBL10090875 0.92 PTPN11 (0.52) PTPN11RARBPTPN1NR5A1PDK2
SCHEMBL1630438 0.92 PTPN11 (0.52) PTPN11RARBPTPN1NR5A1PDK2
SCHEMBL10090891 0.92 PTPN11 (0.52) PTPN11RARBPTPN1NR5A1PDK2
SCHEMBL5550301 0.92 PTPN11 (0.52) PTPN11RARBPTPN1NR5A1PDK2
SCHEMBL31425691 0.92 PTPN11 (0.52) PTPN11RARBPTPN1NR5A1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105419207-A Thermoplastic resin film SUMITOMO CHEMICAL CO 2016-03-23 CN disclosed
CN-102421856-B UV-curable protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG 2014-08-27 CN disclosed
US-20120251935-A1 TONER FOR ELECTROPHOTOGRAPHY, DEVELOPER FOR ELECTROPHOTOGRAPHY, TONER CARTRIDGE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD FUJI XEROX CO., LTD. (JP) 2012-10-04 US disclosed
CN-102421856-A UV-curable protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG 2012-04-18 CN disclosed
US-7303846-B2 Electrophotographic toner, process for producing the same, and process for forming image FUJI XEROX CO., LTD. (JP) 2007-12-04 US disclosed
US-20060046173-A1 Electrophotographic toner, process for producing the same, and process for forming image FUJI XEROX CO., LTD. (JP) 2006-03-02 US disclosed