Levulinic Acid

Levulinic Acid

SCHEMBL535036

CC(=O)CCC(=O)[O-].CCCCc1[nH]cc[n+]1C

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 2/20 0.33
GPR84 Q9NQS5 2/20 0.32
POLB P06746 1/20 0.31
FFAR3 O14843 2/20 0.31
HDAC3 O15379 2/20 0.31
HDAC1 Q13547 2/20 0.31
HDAC2 Q92769 2/20 0.31
HDAC8 Q9BY41 2/20 0.31
FABP3 P05413 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL526832 0.90 FFAR3 (0.41) CA1CA2GPR84FFAR3HDAC3
Acetic Acid SCHEMBL232563 0.89 GPR84 (0.33) GPR84POLB
Propionic Acid SCHEMBL528118 0.87 GPR84 (0.36) CA1CA2GPR84
Beta-Alanine SCHEMBL16346339 0.86 CA1 (0.35) CA1CA2GPR84FFAR3HDAC3
Levulinic Acid SCHEMBL535193 0.86 FFAR3 (0.31) FFAR3HDAC3HDAC1HDAC2HDAC8
Bicarbonate SCHEMBL1490995 0.86 ALDH1A1 (0.34) GPR84
Acetic Acid SCHEMBL15575254 0.83 GPR84 (0.38) CA1CA2GPR84
Acetic Acid SCHEMBL1660879 0.83 GPR84 (0.38) CA1CA2GPR84
SCHEMBL2719750 0.82 ALDH1A1 (0.31) CA1CA2GPR84POLB
SCHEMBL535111 0.82 CA1 (0.34) CA1CA2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414476-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. du Pont de Nemours and Company (US) 2012-02-08 EP claimed
WO-2010117836-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO claimed
WO-2010065606-A2 PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 WO claimed
EP-2414476-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. du Pont de Nemours and Company (US) 2012-02-08 EP disclosed
WO-2010117836-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO disclosed
WO-2010065606-A2 PROCESS FOR FERMENTIVE PREPARATION OF ALCOHOLS AND RECOVERY OF PRODUCT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 WO disclosed