SCHEMBL5350366

SCHEMBL5350366

Nc1cc2[nH]c(=O)[nH]c(=O)c2cc1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.55
CA9 Q16790 2/20 0.55
MAPT P10636 6/20 0.46
TSHR P16473 3/20 0.46
HPGD P15428 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP1A2 P05177 2/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
LMNA P02545 1/20 0.46
GRIK1 P39086 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
GRIA4 P48058 1/20 0.46
BLM P54132 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIK2 Q13002 1/20 0.46
GRIK3 Q13003 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5359827 0.93 CA12 (0.55) CA12CA9MAPTTSHRHPGD
SCHEMBL8129404 0.88 MAPT (0.60) CA12CA9MAPTTSHRHPGD
SCHEMBL12314591 0.84 MAPT (0.59) CA12CA9MAPTTSHRHPGD
SCHEMBL8135744 0.82 CA12 (0.57) CA12CA9MAPTTSHRHPGD
SCHEMBL7482757 0.79 GRIA2 (0.74) MAPTTSHRHPGDCYP3A4CYP1A2
SCHEMBL8137077 0.79 CA12 (0.54) CA12CA9MAPTTSHRHPGD
SCHEMBL8136133 0.79 CA12 (0.54) CA12CA9MAPTTSHRHPGD
SCHEMBL8141475 0.79 CA12 (0.54) CA12CA9MAPTTSHRHPGD
SCHEMBL3827659 0.75 KDM4E (0.67) CA12CA9MAPTTSHRHPGD
SCHEMBL14891075 0.74 KDM4E (0.64) CA12CA9MAPTTSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7262284-B2 Method for producing disazo pigments CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-28 US disclosed
US-20060167236-A1 Method for producing disazo pigments CLARIANT GMBH (DE) 2006-07-27 US disclosed
EP-1517962-A1 METHOD FOR PRODUCING DISAZO PIGMENTS Clariant GmbH (DE) 2005-03-30 EP disclosed
WO-2004000947-A1 METHOD FOR PRODUCING DISAZO PIGMENTS CLARIANT GMBH (DE) 2003-12-31 WO disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
EP-0518909-B1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AG (DE) 1994-05-25 EP disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0518909-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. HOECHST AG (DE) 1992-12-23 EP disclosed
EP-0316649-B1 WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP disclosed
WO-1991013941-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-19 WO disclosed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
EP-0316649-A2 Water insoluble azo colouring agents, their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167236-A1 Method for producing disazo pigments TYR, IPO4, CBR3 CA12 1138/4885CA9 1804/4885MAPT 1879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.