Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350472 | 1.00 | ENPP2 (0.50) | ENPP2RPS6KA3EGFRCA2CA12 | |
| SCHEMBL5357284 | 0.93 | ENPP2 (0.53) | ENPP2RPS6KA3EGFRCA2CA12 | |
| SCHEMBL5357289 | 0.93 | ENPP2 (0.53) | ENPP2RPS6KA3EGFRCA2CA12 | |
| SCHEMBL10624387 | 0.85 | EGFR (0.62) | EGFRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10604233 | 0.85 | EGFR (0.62) | EGFRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11316218 | 0.85 | EGFR (0.62) | EGFRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11316220 | 0.85 | EGFR (0.62) | EGFRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10624379 | 0.85 | EGFR (0.62) | EGFRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL16153074 | 0.84 | EGFR (0.66) | EGFRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14690238 | 0.84 | EGFR (0.66) | EGFRMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197699-A1 | Novel substituted-polyaryl chromophoric compounds | TRANSPHOTONICS, LLC (US) | 2007-08-23 | — | — | US | disclosed |
| US-7205347-B2 | Substituted-polyaryl chromophoric compounds | TRANS PHOTONICS, LLC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20040013375-A1 | Novel substituted-polyaryl chromophoric compounds | TRANS PHOTONICS, L.L.C. | 2004-01-22 | — | — | US | disclosed |
| WO-2002033005-A2 | NOVEL SUBSTITUTED-POLYARYL CHROMOPHORIC COMPOUNDS | TRANS PHOTONICS, L.L.C. (US) | 2002-04-25 | — | — | WO | disclosed |