SCHEMBL5350640

SCHEMBL5350640

Cc1cc2c(cc1C(=O)Nc1ccccc1)C(C1CCCCC1)=NN(C(C)C)C(=O)N2c1ccc(CC2=NCCN2)cc1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 16/20 0.66
CCKBR P32239 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5356554 0.87 PTH1R (0.67) PTH1R
SCHEMBL5368169 0.84 PTH1R (0.69) PTH1R
SCHEMBL5324368 0.82 PTH1R (0.67) PTH1R
SCHEMBL5362367 0.82 PTH1R (0.84) PTH1R
SCHEMBL5363635 0.81 PTH1R (0.82) PTH1R
SCHEMBL5367699 0.80 PTH1R (0.76) PTH1R
SCHEMBL5487298 0.80 PTH1R (0.67) PTH1R
SCHEMBL14386442 0.80 PTH1R (0.83) PTH1R
SCHEMBL5376690 0.79 PTH1R (0.74) PTH1R
SCHEMBL5355799 0.79 PTH1R (0.98) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007135417-A1 BENZOTRIAZEPINONE DERIVATIVES JAMES BLACK FOUNDATION (GB) 2007-11-29 WO disclosed