Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 19/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350903 | 1.00 | PTH1R (0.55) | PTH1RLMNACYP1A2ADRA2ACYP2D6 | |
| SCHEMBL5352412 | 0.85 | PTH1R (0.56) | PTH1RLMNACYP1A2ADRA2ACYP2D6 | |
| SCHEMBL5349639 | 0.85 | PTH1R (0.47) | PTH1R | |
| SCHEMBL5349636 | 0.85 | PTH1R (0.47) | PTH1R | |
| SCHEMBL5353466 | 0.84 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5359824 | 0.82 | PTH1R (0.67) | PTH1R | |
| SCHEMBL5368169 | 0.76 | PTH1R (0.69) | PTH1RLMNACYP1A2ADRA2ACYP2D6 | |
| SCHEMBL5356554 | 0.75 | PTH1R (0.67) | PTH1R | |
| SCHEMBL5324368 | 0.75 | PTH1R (0.67) | PTH1RLMNACYP1A2ADRA2ACYP2D6 | |
| SCHEMBL5350640 | 0.74 | PTH1R (0.66) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |