SCHEMBL5351233

SCHEMBL5351233

CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](NC(=O)Nc3ccccc3)[C@H]2O)[C@H](O)[C@H]1NC(C)=O

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LGALS3 P17931 9/20 0.71
▸ LGALS7; LGALS7B P47929 4/20 0.69
▸ LGALS1 P09382 2/20 0.69
▸ LGALS9 O00182 4/20 0.56
▸ LGALS8 O00214 1/20 0.48
▸ LGALS4 P56470 1/20 0.48
▸ POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5351236 1.00 LGALS3 (0.71) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8
SCHEMBL5356738 0.88 LGALS3 (0.82) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8
SCHEMBL5356735 0.88 LGALS3 (0.82) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8
SCHEMBL5354309 0.86 LGALS3 (0.84) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8
SCHEMBL5354301 0.86 LGALS3 (0.84) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8
SCHEMBL17097341 0.86 LGALS3 (0.84) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8
SCHEMBL19976155 0.84 LGALS3 (0.68) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8
SCHEMBL19976166 0.83 LGALS3 (1.00) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8
SCHEMBL17681092 0.83 LGALS3 (1.00) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8
SCHEMBL19976179 0.82 LGALS3 (0.79) LGALS3LGALS7; LGALS7BLGALS1LGALS9LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150265701-A1 IMMUNOMODULATING COMPOSITIONS AND USES THEREFOR CANCURE LIMITED ACN 164 438 359 (AU) 2015-09-24 — — US claimed
US-20070207161-A1 Immunomodulating Compositions and uses Therefor CANCURE LIMITED ACN 164 438 359 (AU) 2007-09-06 — — US claimed
US-7230096-B2 Inhibitors against galectins FORSKARPATENT I SYD AB (SE) 2007-06-12 — — US claimed
US-20040147730-A1 Inhibitors against galectins FORSKARPATENT I SYD AB (SE) 2004-07-29 — — US claimed
US-9770503-B2 Immunomodulating compositions and uses therefor CANCURE LIMITED ACN 164 438 359 (AU) 2017-09-26 — — US disclosed
US-20150320782-A1 Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-11-12 — — US disclosed
US-20150265701-A1 IMMUNOMODULATING COMPOSITIONS AND USES THEREFOR CANCURE LIMITED ACN 164 438 359 (AU) 2015-09-24 — — US disclosed
US-9050352-B2 Immunomodulating compositions and uses therefor CANCURE LIMITED ACN 164 438 359 (AU) 2015-06-09 — — US disclosed
EP-2591786-A1 Immunomodulating compositions and uses therefor Ralph, Stephen John (AU) 2013-05-15 — — EP disclosed
US-20070207161-A1 Immunomodulating Compositions and uses Therefor CANCURE LIMITED ACN 164 438 359 (AU) 2007-09-06 — — US disclosed
US-7230096-B2 Inhibitors against galectins FORSKARPATENT I SYD AB (SE) 2007-06-12 — — US disclosed
US-20040147730-A1 Inhibitors against galectins FORSKARPATENT I SYD AB (SE) 2004-07-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147730-A1 Inhibitors against galectins LGALS1, LGALS3, LGALS2 LGALS3 2/4885LGALS7; LGALS7B 8/4885LGALS1 1/4885
US-20150320782-A1 Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor LGALS1, LGALS2, LGALS3BP LGALS3 4/4885LGALS7; LGALS7B 8/4885LGALS1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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