SCHEMBL5351701

SCHEMBL5351701

CCC1=Cc2c(CC)cccc2C1[Zr](Cl)(Cl)(C1C(CC)=Cc2c(CC)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5951141 0.88 CSNK2A2 (0.32)
SCHEMBL5951549 0.88 GABRA1 (0.34) GABRA1GABRB2
SCHEMBL5952076 0.88
SCHEMBL4078128 0.87 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL5953084 0.87
SCHEMBL5953100 0.87 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL5346836 0.85 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL4073954 0.85
SCHEMBL7189978 0.84
SCHEMBL2517396 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 EP claimed
EP-1058694-B1 Catalyst system, method for its production and its use for the polymerisation of olefins BASELL POLYOLEFINE GMBH (DE) 2003-04-09 EP claimed
US-6482902-B1 Catalyst system TARGOR GMBH (DE) 2002-11-19 US claimed
US-6391989-B1 COORDINATION CATALYST ON SUPPORT; POLYMERIZATION OF ALPHA-OLEFINS BASELL POLYPROPYLEN GMBH (DE) 2002-05-21 US claimed
WO-2014070655-A1 SUPPORTED METALLOCENE CATALYST SYSTEMS AND METHODS OF PREPARATION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-05-08 WO disclosed
US-20140121341-A1 Supported Metallocene Catalyst Systems and Methods of Preparation Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2014-05-01 US disclosed
US-7202190-B1 Supported catalyst system for the polymerization of olefins TARGOR GMBH (DE) 2007-04-10 US disclosed
US-7101940-B2 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-09-05 US disclosed
US-7034173-B2 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-04-25 US disclosed
US-6953829-B2 Catalyst system and the use thereof BASELL POLYOLEFINE GMBH (DE) 2005-10-11 US disclosed
US-6949614-B1 Catalyst system BASELL POLYOLEFINE GMBH (DE) 2005-09-27 US disclosed
US-6900343-B1 Method for the purification of metallocenes BASELL POLYOLEFINE GMBH (DE) 2005-05-31 US disclosed
US-6482902-B1 Catalyst system TARGOR GMBH (DE) 2002-11-19 US disclosed
US-6417302-B1 REACTION PRODUCT OF DI(PENTAFLUOROPHENYL) BORINIC ACID AND ORGANOALUMINUM COMPOUND; OLEFIN POLYMERIZATION COORDINATION CATALYSTS BASELL POLYOLEFINE GMBH (DE) 2002-07-09 US disclosed
US-6407189-B1 USING ORGANOMETALLIC COMPOUNDS AS CATALYST CLARIANT GMBH (DE) 2002-06-18 US disclosed
US-6391989-B1 COORDINATION CATALYST ON SUPPORT; POLYMERIZATION OF ALPHA-OLEFINS BASELL POLYPROPYLEN GMBH (DE) 2002-05-21 US disclosed
US-20020058765-A1 Catalyst system for the polymerization of olefins BAYER AKTIENGESELLSCHAFT (DE) 2002-05-16 US disclosed
US-6271164-B1 METALLOCENE CATALYST LYONDELL CHEMICAL TECHNOLOGY, L.P. 2001-08-07 US disclosed
US-6177526-B1 METALLOCENE; COCATALYST; MODIFIED OXIDE CONTAINS ORGANIC SILICON RADICALS CONTAINING AT LEAST ONE OF THE GROUPS NITROGEN, FLUORINE, PHOSPHORUS OR SULFUR. TARGOR GMBH (DE) 2001-01-23 US disclosed
US-6177376-B1 REACTING METALLOCENE WITH ORGANOLITHIUM COMPOUND AND GRIGNARD COMPOUND, ACTIVATION, CONTACTING WITH SUPPORT TARGOR GMBH (DE) 2001-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058765-A1 Catalyst system for the polymerization of olefins MAOA, MAOB, MSMO1 GABRA1 2975/4885GABRB2 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.