SCHEMBL5351735

SCHEMBL5351735

CCC[C@H]1CC[C@H](c2ccc(OC)cc2)CC1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.58
CYP2C9 P11712 1/20 0.56
MAPT P10636 3/20 0.54
ALDH1A1 P00352 2/20 0.54
LMNA P02545 1/20 0.54
MEN1 O00255 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
ESR2 Q92731 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.42
KDM1A O60341 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
CHRM4 P08173 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5351739 1.00 DRD2 (0.58) DRD2CYP2C9MAPTALDH1A1LMNA
SCHEMBL8045452 0.95 DRD2 (0.54) DRD2CYP2C9MAPTALDH1A1LMNA
SCHEMBL7903735 0.95 DRD2 (0.54) DRD2CYP2C9MAPTALDH1A1LMNA
SCHEMBL8045462 0.95 DRD2 (0.54) DRD2CYP2C9MAPTALDH1A1LMNA
SCHEMBL9258676 0.95 DRD2 (0.54) DRD2CYP2C9MAPTALDH1A1LMNA
SCHEMBL9258683 0.95 DRD2 (0.54) DRD2CYP2C9MAPTALDH1A1LMNA
SCHEMBL21456800 0.92 DRD2 (0.51) DRD2CYP2C9MAPTALDH1A1LMNA
SCHEMBL5343187 0.91 DRD2 (0.50) DRD2CYP2C9MAPTALDH1A1LMNA
SCHEMBL13621706 0.91 DRD2 (0.50) DRD2CYP2C9MAPTALDH1A1LMNA
SCHEMBL8368584 0.90 DRD2 (0.55) DRD2CYP2C9MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119555817-A Pretreatment method for efficiently extracting trace liquid crystal monomer from water based on membrane filtration technology 南京理工大学 2025-03-04 CN claimed
CN-119555817-A Pretreatment method for efficiently extracting trace liquid crystal monomer from water based on membrane filtration technology 南京理工大学 2025-03-04 CN disclosed
US-7186447-B2 Two plane parallel support plates with frame form cell, with integrated non-linear elements for switching individual picture elements on support plates, and nematic liquid crystal mixture is present in cell, having positive dielectric anisotropy and high resistivity MERCK PATENT GMBH (DE) 2007-03-06 US disclosed
US-7045176-B2 Liquid crystal composition having high-speed response property and liquid crystal display using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-05-16 US disclosed
US-6905740-B2 The invention relates to a matrix liquid crystal display containing integrated non-linear elements and a liquid crystal mixture which has a particularly high resistivity. MERCK PATENT GMBH (DE) 2005-06-14 US disclosed
EP-1501830-A1 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES Actelion Pharmaceuticals Ltd. (CH) 2005-02-02 EP disclosed
US-20040119051-A1 Liquid crystal composition having high-speed response property and liquid crystal display using the same SAMSUNG ELECTRONICS CO., LTD. 2004-06-24 US disclosed
WO-2003093267-A1 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES ACTELION PHARMACEUTICALS LTD (CH) 2003-11-13 WO disclosed
US-20030207046-A1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-11-06 US disclosed
US-6562419-B1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-05-13 US disclosed
EP-0155317-B1 LIQUID CRYSTAL MIXTURES AND NEW ANISOTROPIC COMPOUNDS THEREFOR MERCK PATENT GmbH (DE) 1987-07-08 EP disclosed
EP-0226592-A1 LIQUID CRYSTAL PHASE. MERCK PATENT GMBH (DE) 1987-07-01 EP disclosed
EP-0215800-A1 PYRIMIDINES. MERCK PATENT GMBH (DE) 1987-04-01 EP disclosed
WO-1986005799-A1 LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-10-09 WO disclosed
WO-1986004060-A1 PYRIMIDINES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-07-17 WO disclosed
EP-0158252-A2 Liquid crystal phase MERCK PATENT GmbH (DE) 1985-10-16 EP disclosed
EP-0155317-A1 LIQUID CRYSTAL MIXTURES AND NEW ANISOTROPIC COMPOUNDS THEREFOR. MERCK PATENT GMBH (DE) 1985-09-25 EP disclosed
EP-0151446-A2 Liquid crystal phase MERCK PATENT GmbH (DE) 1985-08-14 EP disclosed
WO-1985001295-A1 LIQUID CRYSTAL MIXTURES AND NEW ANISOTROPIC COMPOUNDS THEREFOR MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1985-03-28 WO disclosed
EP-0118061-A2 Liquid crystal guest host systems MERCK PATENT GmbH (DE) 1984-09-12 EP disclosed