SCHEMBL9258683

SCHEMBL9258683

CCCC1CCC(c2ccc(-c3ccc(OC)cc3)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.54
CYP2C9 P11712 1/20 0.52
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.50
MAPK1 P28482 2/20 0.50
KMT2A Q03164 2/20 0.50
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.42
DGAT1 O75907 1/20 0.42
ESR2 Q92731 2/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9258676 1.00 DRD2 (0.54) DRD2CYP2C9ALDH1A1MAPTMEN1
SCHEMBL5351735 0.95 DRD2 (0.58) DRD2CYP2C9ALDH1A1MAPTMEN1
SCHEMBL5351739 0.95 DRD2 (0.58) DRD2CYP2C9ALDH1A1MAPTMEN1
SCHEMBL14030488 0.93 DRD2 (0.48) DRD2CYP2C9ALDH1A1MAPTMEN1
SCHEMBL9509299 0.92 DRD2 (0.47) DRD2CYP2C9ALDH1A1MAPTMEN1
SCHEMBL11281659 0.91 DRD2 (0.51) DRD2CYP2C9ALDH1A1MAPTMEN1
SCHEMBL8045462 0.91 DRD2 (0.54) DRD2CYP2C9ALDH1A1MAPTMEN1
SCHEMBL7903735 0.91 DRD2 (0.54) DRD2CYP2C9ALDH1A1MAPTMEN1
SCHEMBL8045452 0.91 DRD2 (0.54) DRD2CYP2C9ALDH1A1MAPTMEN1
SCHEMBL14048287 0.91 DRD2 (0.46) DRD2CYP2C9ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-20200172811-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2020-06-04 US disclosed
US-20180187079-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-07-05 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-9963636-B2 Liquid crystal composition and liquid crystal display device using same DIC CORPORATION (JP) 2018-05-08 US disclosed
US-9938463-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2018-04-10 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-20100149950-A1 LIQUID CRYSTAL OPTICAL MODULATION ELEMENT AND OPTICAL HEAD DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2010-06-17 US disclosed
US-7618554-B2 for in-plane switching (IPS) liquid crystal displays and low voltage-driven twist nematic (TN) liquid crystal displays and has a high dielectric anisotropy and a low rotational viscosity; perfluoroallyl difluorophenyl ethers ADEKA CORPORATION (JP) 2009-11-17 US disclosed
US-7442418-B2 Polymerizable liquid crystal compound, liquid crystal composition, optical anisotropic material and optical element ASAHI GLASS COMPANY, LIMITED (JP) 2008-10-28 US disclosed
US-20080231788-A1 LIQUID CRYSTAL OPTICAL MODULATION ELEMENT AND OPTICAL HEAD DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2008-09-25 US disclosed
US-20080149890-A1 Liquid Crystal Composition ADEKA CORPORATION (JP) 2008-06-26 US disclosed
US-20070104894-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIC MATERIAL AND OPTICAL ELEMENT ASAHI GLASS CO., LTD. (JP) 2007-05-10 US disclosed
US-5454975-A Electrooptical display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-10-03 US disclosed
EP-0022183-B1 DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS MERCK PATENT GmbH (DE) 1982-06-23 EP disclosed
US-4330426-A Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-18 US disclosed
EP-0022183-A2 Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements MERCK PATENT GmbH (DE) 1981-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 DRD2 271/4885CYP2C9 3955/4885ALDH1A1 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.