Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318228 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MAPTTDP1NPSR1PKM | |
| SCHEMBL5321492 | 0.79 | MAPT (1.00) | ALDH1A1MAPTTDP1NPSR1PKM | |
| SCHEMBL5321349 | 0.72 | ALOX15 (0.53) | ALDH1A1MAPTTDP1SMN1; SMN2KDM4E | |
| SCHEMBL14685052 | 0.70 | SMN1; SMN2 (0.65) | ALDH1A1MAPTTDP1SMN1; SMN2KDM4E | |
| SCHEMBL4502100 | 0.70 | HAVCR2 (0.40) | ALDH1A1MAPTTDP1PKMSMN1; SMN2 | |
| SCHEMBL5321360 | 0.70 | MEN1 (0.57) | ALDH1A1MAPTTDP1NPSR1SMN1; SMN2 | |
| SCHEMBL5321338 | 0.70 | CXCR2 (0.47) | ALDH1A1MAPTPKMSMN1; SMN2TAAR1 | |
| SCHEMBL5649167 | 0.70 | CXCR2 (0.51) | MAPTTDP1SMN1; SMN2TAAR1CYP1A2 | |
| SCHEMBL5321476 | 0.70 | DAO (0.40) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL1197584 | 0.69 | TAAR1 (1.00) | ALDH1A1TDP1NPSR1SMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |