SCHEMBL5352001

SCHEMBL5352001

O=C1c2ccccc2C(=O)N1c1ccc(N2C(=O)c3ccccc3C2=O)c(O)c1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 3/20 0.64
PIM3 Q86V86 1/20 0.64
HIPK4 Q8NE63 1/20 0.64
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
NR1H3 Q13133 5/20 0.53
CA9 Q16790 3/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
NR1H2 P55055 1/20 0.50
ESR1 P03372 4/20 0.49
ESR2 Q92731 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12733162 0.83 ESR1 (0.51) SCN2APIM3HIPK4NR1H3NR1H2
SCHEMBL9240516 0.81 CYP3A4 (0.66) SCN2APIM3HIPK4KMT2AMEN1
SCHEMBL10597675 0.81 MEN1 (0.72) SCN2APIM3HIPK4KMT2AMEN1
SCHEMBL7514060 0.81 MEN1 (0.49) SCN2APIM3HIPK4KMT2AMEN1
SCHEMBL7360730 0.81 SCN2A (0.62) SCN2APIM3HIPK4KMT2AMEN1
SCHEMBL3790877 0.79 KMT2A (0.56) SCN2APIM3HIPK4KMT2AMEN1
Hydrochloric Acid SCHEMBL29690161 0.79 CYP3A4 (0.64) SCN2APIM3HIPK4KMT2AMEN1
SCHEMBL2150841 0.79 MEN1 (0.55) SCN2APIM3HIPK4KMT2AMEN1
SCHEMBL38651889 0.78 SCN2A (1.00) SCN2APIM3HIPK4KMT2AMEN1
SCHEMBL28482977 0.77 MEN1 (0.72) SCN2APIM3HIPK4KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2341392-A1 Electrophotographic photosensitive body Hodogaya Chemical Co., Ltd. (JP) 2011-07-06 EP disclosed
US-20070197699-A1 Novel substituted-polyaryl chromophoric compounds TRANSPHOTONICS, LLC (US) 2007-08-23 US disclosed
US-7205347-B2 Substituted-polyaryl chromophoric compounds TRANS PHOTONICS, LLC. (US) 2007-04-17 US disclosed
US-20040013375-A1 Novel substituted-polyaryl chromophoric compounds TRANS PHOTONICS, L.L.C. 2004-01-22 US disclosed
EP-1181288-B1 BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT UPJOHN CO (US) 2003-07-30 EP disclosed
US-6387896-B1 GRAMNEGATIVE, GRAMPOSITVE BACTERIA PHARMACIA & UPJOHN CO. 2002-05-14 US disclosed
WO-2002033005-A2 NOVEL SUBSTITUTED-POLYARYL CHROMOPHORIC COMPOUNDS TRANS PHOTONICS, L.L.C. (US) 2002-04-25 WO disclosed