SCHEMBL7360730

SCHEMBL7360730

O=C1c2ccccc2C(=O)N1c1ccc(F)c(O)c1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 3/20 0.62
PIM3 Q86V86 1/20 0.62
HIPK4 Q8NE63 1/20 0.62
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
NR1H3 Q13133 5/20 0.51
NR1H2 P55055 1/20 0.49
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
ESR1 P03372 3/20 0.47
GRM1 Q13255 1/20 0.47
ESR2 Q92731 1/20 0.46
PPARG P37231 1/20 0.45
PPARD Q03181 1/20 0.45
PPARA Q07869 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5352001 0.81 SCN2A (0.64) SCN2APIM3HIPK4MEN1KMT2A
SCHEMBL10999030 0.79 KMT2A (0.62) SCN2APIM3HIPK4MEN1KMT2A
SCHEMBL10597675 0.79 MEN1 (0.72) SCN2APIM3HIPK4MEN1KMT2A
SCHEMBL38651889 0.77 SCN2A (1.00) SCN2APIM3HIPK4MEN1KMT2A
SCHEMBL29155400 0.77 MGLL (0.53) CA9
SCHEMBL12835328 0.76 SCN2A (0.58) SCN2APIM3HIPK4MEN1KMT2A
SCHEMBL28482977 0.76 MEN1 (0.72) SCN2APIM3HIPK4MEN1KMT2A
SCHEMBL6676671 0.76 KMT2A (0.72) SCN2APIM3HIPK4MEN1KMT2A
SCHEMBL2574766 0.76 SCN2A (0.57) SCN2APIM3HIPK4MEN1KMT2A
SCHEMBL6638165 0.76 SCN2A (0.75) SCN2APIM3HIPK4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179026-A4 BRANCHED AND HYPERBRANCHED POLYETHERIMIDES FROM STABLE A1Bn, AB, AA, AND BB MONOMERS; AM ENDCAPPING AGENTS UNIV ILLINOIS (US) 2003-04-02 EP disclosed
EP-1179026-A1 BRANCHED AND HYPERBRANCHED POLYETHERIMIDES FROM STABLE A1Bn, AB, AA, AND BB MONOMERS; AM ENDCAPPING AGENTS The Board of Trustees for the University of Illinois (US) 2002-02-13 EP disclosed
US-6333390-B1 HIGH SOLUBILITY AND LOW VISCOSITY, THERMALLY AND CHEMICALLY STABLE, REACTING AN AMINO-PHENOL WITH AN AROMATIC ANHYDRIDE, MIXING THE RESULTING ARYLIMIDE WITH A SILYL ELECTROPHILE AND A BASE, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2001-12-25 US disclosed
WO-2000026267-A9 BRANCHED AND HYPERBRANCHED POLYETHERIMIDES FROM STABLE A1Bn, AB, AA, AND BB MONOMERS; AM ENDCAPPING AGENTS UNIV ILLINOIS (US) 2000-10-19 WO disclosed
WO-2000026267-A1 BRANCHED AND HYPERBRANCHED POLYETHERIMIDES FROM STABLE A1Bn, AB, AA, AND BB MONOMERS; AM ENDCAPPING AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2000-05-11 WO disclosed