Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834631 | 0.96 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAATML3MBTL1 | |
| SCHEMBL6773443 | 0.85 | KMT2A (0.54) | ALDH1A1KDM4ELMNAATML3MBTL1 | |
| SCHEMBL3835347 | 0.81 | GPR139 (0.52) | ATMMEN1KMT2AGPR139 | |
| SCHEMBL7197279 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4ELMNAL3MBTL1MEN1 | |
| SCHEMBL348441 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAL3MBTL1MEN1 | |
| SCHEMBL6773591 | 0.77 | GPR139 (0.53) | ALDH1A1KDM4ELMNAATMMEN1 | |
| SCHEMBL3839471 | 0.76 | GPR139 (0.47) | ATMMEN1KMT2AGPR139 | |
| SCHEMBL6778751 | 0.76 | GPR139 (0.47) | ALDH1A1ATMMEN1KMT2AGPR139 | |
| SCHEMBL6773780 | 0.75 | NAMPT (0.49) | ALDH1A1LMNAL3MBTL1HTTMAPT | |
| SCHEMBL27485172 | 0.75 | ATM (0.53) | ALDH1A1KDM4ELMNAATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220824-B1 | Integrin-mediated drug targeting | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |