Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358989 | 0.91 | LMNA (0.44) | LMNAMAPTSMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL5358758 | 0.82 | MAPT (0.36) | LMNAMAPTSMN1; SMN2AOC3ALDH1A1 | |
| SCHEMBL5361944 | 0.82 | AOC3 (0.45) | LMNAMAPTSMN1; SMN2FABP4NPSR1 | |
| SCHEMBL5352377 | 0.80 | SMN1; SMN2 (0.39) | LMNAMAPTSMN1; SMN2FABP4NPSR1 | |
| SCHEMBL5354253 | 0.74 | LMNA (0.48) | LMNAMAPTSMN1; SMN2AOC3ALDH1A1 | |
| SCHEMBL5356444 | 0.74 | GBA1 (0.37) | LMNASMN1; SMN2AOC3ALDH1A1 | |
| SCHEMBL5360895 | 0.73 | AOC3 (0.34) | LMNASMN1; SMN2AOC3ALDH1A1 | |
| SCHEMBL5356604 | 0.72 | LMNA (0.46) | LMNAMAPTSMN1; SMN2FABP4NPSR1 | |
| SCHEMBL5358993 | 0.72 | KCNH2 (0.41) | LMNAMAPTSMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL5359283 | 0.69 | BACE1 (0.34) | NPSR1HPGDALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20050227959-A1 | Heterocyclic compound having oxime group | EISAI CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227959-A1 | Heterocyclic compound having oxime group | STAT6, HRH4, HRH2 | LMNA 4744/4885MAPT 4554/4885SMN1; SMN2 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.