Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 8/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360895 | 0.86 | AOC3 (0.34) | GBA1AOC3CCR5ALDH1A1KDM4E | |
| SCHEMBL5352376 | 0.74 | LMNA (0.38) | AOC3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5358989 | 0.73 | LMNA (0.44) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5358758 | 0.69 | MAPT (0.36) | AOC3CCR5ALDH1A1LMNAKMT2A | |
| SCHEMBL5357321 | 0.64 | HDAC4 (0.42) | GBA1AOC3ALDH1A1KDM4EHDAC4 | |
| SCHEMBL5215845 | 0.63 | AOC3 (0.44) | AOC3ALDH1A1HTT | |
| SCHEMBL5354321 | 0.62 | KMT2A (0.51) | AOC3ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5358993 | 0.61 | KCNH2 (0.41) | ALDH1A1LMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5350841 | 0.61 | AOC3 (0.41) | AOC3ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5350840 | 0.60 | AOC3 (0.42) | AOC3ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20050227959-A1 | Heterocyclic compound having oxime group | EISAI CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227959-A1 | Heterocyclic compound having oxime group | STAT6, HRH4, HRH2 | GBA1 1567/4885AOC3 522/4885CCR5 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.