Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345725 | 0.99 | ALDH1A1 (0.77) | ALDH1A1LMNAATMCYP2C9TP53 | |
| SCHEMBL4611550 | 0.78 | ALDH1A1 (0.49) | ALDH1A1LMNATP53TSHRGAA | |
| SCHEMBL14968041 | 0.69 | ALDH1A1 (0.53) | ALDH1A1LMNACYP2C9TSHRMAPT | |
| SCHEMBL14967474 | 0.68 | ALDH1A1 (0.55) | ALDH1A1LMNACYP2C9MEN1KMT2A | |
| SCHEMBL2027200 | 0.66 | ALDH1A1 (0.49) | ALDH1A1LMNACYP2C9TSHRMEN1 | |
| SCHEMBL1634434 | 0.66 | ALDH1A1 (0.49) | ALDH1A1LMNATP53TSHRHTT | |
| SCHEMBL28270854 | 0.66 | ALDH1A1 (0.49) | ALDH1A1LMNACYP2C9HPGDHSD17B10 | |
| SCHEMBL1635709 | 0.65 | ALDH1A1 (0.51) | ALDH1A1LMNATP53KDM4EMEN1 | |
| SCHEMBL18274527 | 0.64 | LMNA (0.50) | ALDH1A1LMNATP53TSHRHTT | |
| SCHEMBL18274526 | 0.64 | LMNA (0.50) | ALDH1A1LMNATP53TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183423-B1 | Process for the preparation of organic compounds with imide catalysts | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1055654-A1 | PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS | Daicel Chemical Industries, Ltd. (JP) | 2000-11-29 | — | — | EP | disclosed |