Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352809 | 1.00 | PARP10 (0.35) | PARP10L3MBTL1NPC1LMNARAB9A | |
| SCHEMBL15865998 | 0.74 | SMN1; SMN2 (0.46) | PARP10L3MBTL1NPC1LMNARAB9A | |
| SCHEMBL9945281 | 0.73 | SMN1; SMN2 (0.43) | PARP10L3MBTL1NPC1LMNARAB9A | |
| SCHEMBL25119945 | 0.72 | L3MBTL1 (0.44) | PARP10L3MBTL1NPC1LMNARAB9A | |
| SCHEMBL9944318 | 0.69 | NPC1 (0.42) | PARP10L3MBTL1NPC1LMNARAB9A | |
| SCHEMBL6820484 | 0.69 | SYK (0.39) | PARP10SMN1; SMN2SYKAURKBINCENP | |
| SCHEMBL17592449 | 0.66 | HRH1 (0.42) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL11280500 | 0.65 | SMN1; SMN2 (0.54) | PARP10L3MBTL1NPC1LMNARAB9A | |
| SCHEMBL9945448 | 0.63 | SMN1; SMN2 (0.43) | PARP10NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL14075065 | 0.62 | SMN1; SMN2 (0.45) | PARP10NPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099385-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR COMPOUNDS AND COMPOSITIONS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-09-07 | — | — | WO | claimed |