Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 5/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865998 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1LMNARAB9AL3MBTL1 | |
| SCHEMBL9944318 | 0.79 | NPC1 (0.42) | SMN1; SMN2NPC1LMNARAB9AL3MBTL1 | |
| SCHEMBL12072300 | 0.74 | NPC1 (0.46) | SMN1; SMN2NPC1LMNARAB9AL3MBTL1 | |
| SCHEMBL9945413 | 0.74 | NPC1 (0.46) | SMN1; SMN2NPC1LMNARAB9AL3MBTL1 | |
| SCHEMBL5352809 | 0.73 | PARP10 (0.35) | SMN1; SMN2NPC1LMNARAB9AL3MBTL1 | |
| SCHEMBL5352804 | 0.73 | PARP10 (0.35) | SMN1; SMN2NPC1LMNARAB9AL3MBTL1 | |
| SCHEMBL9945448 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1LMNARAB9APARP10 | |
| SCHEMBL14075065 | 0.72 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1LMNARAB9APARP10 | |
| SCHEMBL8472048 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1LMNARAB9APARP10 | |
| SCHEMBL15865983 | 0.71 | ALDH1A1 (0.45) | SMN1; SMN2NPC1LMNARAB9APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149707-A1 | ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | OSCOTEC INC. (KR) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149707-A1 | ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | HIF1A, HIF1AN, EGLN3 | SMN1; SMN2 3764/4885NPC1 3736/4885LMNA 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.