SCHEMBL5352937

SCHEMBL5352937

OC1CCc2cccc(Br)c2C1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 1/20 0.42
TRPV1 Q8NER1 10/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23045125 1.00 CHRM3 (0.42) CHRM3TRPV1
SCHEMBL30308815 0.82 TRPV1 (0.38) TRPV1
SCHEMBL9455952 0.82 TRPV1 (0.38) TRPV1
SCHEMBL4813078 0.79 CHRM3 (0.65) CHRM3
SCHEMBL23045120 0.78 DRD2 (0.50) CHRM3TRPV1
SCHEMBL287422 0.78 SLC18A3 (0.44) CHRM3TRPV1
SCHEMBL205316 0.78 SLC18A3 (0.44) CHRM3TRPV1
SCHEMBL23045121 0.78 TRPV1 (0.45) CHRM3TRPV1
SCHEMBL23045126 0.78 DRD2 (0.50) CHRM3TRPV1
SCHEMBL23045122 0.78 TRPV1 (0.45) CHRM3TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250246-A1 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2025-08-07 US disclosed
US-12286414-B2 Method for producing heterocyclidene acetamide derivative MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2025-04-29 US disclosed
CN-118812481-A Process for producing heterocyclylacetamide derivative 持田制药株式会社 2024-10-22 CN disclosed
EP-4019485-B1 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVES MOCHIDA PHARM CO LTD (JP) 2024-08-07 EP disclosed
EP-4410989-A2 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVES Mochida Pharmaceutical Co., Ltd. (JP) 2024-08-07 EP disclosed
CN-114206847-B Process for producing heterocyclylacetamide derivative 持田制药株式会社 2024-07-16 CN disclosed
EP-4019485-A1 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVES Mochida Pharmaceutical Co., Ltd. (JP) 2022-06-29 EP disclosed
EP-4019485-A1 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVES Mochida Pharmaceutical Co., Ltd. (JP) 2022-06-29 EP disclosed
CN-114206847-A Process for producing heterocyclylideneacetamide derivative 持田制药株式会社 2022-03-18 CN disclosed
US-20220009898-A1 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-01-13 US disclosed
US-20220009898-A1 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-01-13 US disclosed
CN-113563209-A Process for preparing optically active aminoalcohols 持田制药株式会社 2021-10-29 CN disclosed
WO-2021039023-A1 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVES 持田製薬株式会社 2021-03-04 WO disclosed
US-7157463-B2 Substituted piperidines/piperazines as melanocortin receptor agonists ELI LILLY AND COMPANY (US) 2007-01-02 US disclosed
US-20040058936-A1 Substituted piperidines/piperazines as melanocortin receptor agonists ELI LILLY AND COMPANY 2004-03-25 US disclosed
EP-1368339-A1 SUBSTITUTED PIPERIDINES/PIPERAZINES AS MELANOCORTIN RECEPTOR AGONISTS Eli Lilly & Company (US) 2003-12-10 EP disclosed
WO-2002059107-A1 SUBSTITUTED PIPERIDINES/PIPERAZINES AS MELANOCORTIN RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2002-08-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12286414-B2 Method for producing heterocyclidene acetamide derivative COASY, NAAA, AADAC CHRM3 4463/4885TRPV1 2623/4885
US-20040058936-A1 Substituted piperidines/piperazines as melanocortin receptor agonists MC1R, MC4R, MC5R CHRM3 270/4885TRPV1 144/4885
US-20220009898-A1 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVE COASY, NAAA, AADAC CHRM3 4463/4885TRPV1 2623/4885
US-20250250246-A1 METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVE COASY, NAAA, AADAC CHRM3 4463/4885TRPV1 2623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.