Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 15/20 | 0.41 |
| ▸ | AXL | P30530 | 12/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 3/20 | 0.38 |
| ▸ | PRKCA | P17252 | 3/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.38 |
| ▸ | PRKCH | P24723 | 2/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352994 | 1.00 | MERTK (0.41) | MERTKAXLMETTYRO3PRKCB | |
| SCHEMBL5348986 | 0.93 | MERTK (0.41) | MERTKAXLMETTYRO3PRKCB | |
| SCHEMBL5348989 | 0.93 | MERTK (0.41) | MERTKAXLMETTYRO3PRKCB | |
| SCHEMBL5353006 | 0.80 | MAPT (0.38) | — | |
| SCHEMBL4916008 | 0.78 | MAPT (0.50) | MERTKAXL | |
| SCHEMBL4916010 | 0.78 | MAPT (0.50) | MERTKAXL | |
| SCHEMBL14345635 | 0.74 | MERTK (0.49) | MERTKAXLMETTYRO3 | |
| SCHEMBL14345940 | 0.72 | KCNA5 (0.44) | MERTKAXLMETTYRO3KCNA5 | |
| SCHEMBL14184703 | 0.70 | ALDH1A1 (0.51) | MERTKAXLMETTYRO3 | |
| SCHEMBL14345928 | 0.69 | TAS1R3 (0.55) | MERTKAXLMETTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |