Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SAT1 | P21673 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220739 | 0.86 | CYP2C19 (0.50) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL20207809 | 0.81 | CYP2C19 (0.55) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL22856852 | 0.80 | — | — | |
| SCHEMBL10281215 | 0.78 | CYP2C19 (0.57) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL28000379 | 0.77 | CYP2C19 (0.50) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL22374231 | 0.77 | CYP2C19 (0.50) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL20351359 | 0.77 | CYP2C19 (0.50) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL19781407 | 0.77 | CYP2C19 (0.50) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL331540 | 0.77 | CYP2C19 (0.80) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL7089751 | 0.77 | CYP2C19 (0.80) | CYP2C19CYP1A2KDM1AMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232930-B2 | Compounds and methods for preparing methanesulfonamides | PHARMACIA & UPJOHN COMPANY (US) | 2007-06-19 | — | — | US | claimed |
| US-20050148796-A1 | Compounds and methods for preparing methanesulfonamides | PHARMACIA & UPJOHN COMPANY | 2005-07-07 | — | — | US | claimed |
| US-20040167357-A1 | Compounds and methods for preparing methanesulfonamides | PHARMACIA & UPJOHN COMPANY | 2004-08-26 | — | — | US | claimed |
| US-7232930-B2 | Compounds and methods for preparing methanesulfonamides | PHARMACIA & UPJOHN COMPANY (US) | 2007-06-19 | — | — | US | disclosed |
| US-7232930-B2 | Compounds and methods for preparing methanesulfonamides | PHARMACIA & UPJOHN COMPANY (US) | 2007-06-19 | — | — | US | disclosed |
| US-20050148796-A1 | Compounds and methods for preparing methanesulfonamides | PHARMACIA & UPJOHN COMPANY | 2005-07-07 | — | — | US | disclosed |
| US-20040167357-A1 | Compounds and methods for preparing methanesulfonamides | PHARMACIA & UPJOHN COMPANY | 2004-08-26 | — | — | US | disclosed |
| EP-1395549-A1 | COMPOUNDS AND METHODS FOR PREPARING METHANESULFONAMIDES | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002098845-A1 | COMPOUNDS AND METHODS FOR PREPARING METHANESULFONAMIDES | PHARMACIA & UPJOHN COMPANY (US) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148796-A1 | Compounds and methods for preparing methanesulfonamides | HPD, GMDS, ACMSD | CYP2C19 721/4885CYP1A2 466/4885KDM1A 2199/4885 |
| US-20040167357-A1 | Compounds and methods for preparing methanesulfonamides | HACL2, RABL6, FARS2 | CYP2C19 1460/4885CYP1A2 1053/4885KDM1A 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.