Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.59 |
| ▸ | AHR | P35869 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arundine SCHEMBL325162 | 0.76 | MEN1 (1.00) | GPR84AHRMAPTMEN1KMT2A | |
| Tryptamine SCHEMBL28542326 | 0.74 | HTR1D (0.68) | GPR84AHRMAPTMEN1KMT2A | |
| Arundine SCHEMBL28335217 | 0.74 | MEN1 (0.95) | GPR84AHRMAPTMEN1KMT2A | |
| SCHEMBL28684233 | 0.73 | GLA (0.61) | MAPTMEN1KMT2AGLAHTR6 | |
| SCHEMBL25082286 | 0.73 | MEN1 (0.65) | GPR84AHRMAPTMEN1KMT2A | |
| SCHEMBL735576 | 0.73 | GPR84 (0.65) | GPR84AHRMAPTMEN1KMT2A | |
| SCHEMBL31744758 | 0.73 | GPR84 (0.65) | GPR84AHRMAPTMEN1KMT2A | |
| SCHEMBL21163816 | 0.72 | GPR84 (0.57) | GPR84AHRMAPTMEN1KMT2A | |
| SCHEMBL16431196 | 0.72 | GPR84 (0.69) | GPR84AHRMAPTMEN1KMT2A | |
| SCHEMBL9217335 | 0.72 | GPR84 (0.62) | GPR84AHRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129169-A2 | COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL | PFIZER LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |