Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16478 | 0.88 | TSHR (0.70) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL23906770 | 0.88 | TSHR (0.42) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL223907 | 0.88 | TSHR (0.78) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL12147162 | 0.88 | IDO1 (0.52) | TSHRIDO1AGXTRAB9A | |
| Ether SCHEMBL434642 | 0.86 | TSHR (0.50) | TSHRIDO1TP53AGXTALDH1A1 | |
| Bromide SCHEMBL20577438 | 0.86 | TSHR (0.67) | TSHRIDO1TP53AGXTALDH1A1 | |
| Ether SCHEMBL19744986 | 0.86 | TSHR (0.75) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL25430960 | 0.86 | TSHR (0.67) | TSHRIDO1TP53AGXTALDH1A1 | |
| Ether SCHEMBL10609432 | 0.86 | TSHR (0.75) | TSHRIDO1TP53AGXTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL2308512 | 0.86 | TSHR (0.67) | TSHRIDO1TP53AGXTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908601-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | Omeros Corporation (US) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020146795-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | OMEROS CORPORATION (US) | 2020-07-16 | — | — | WO | disclosed |
| US-9760003-B2 | Pattern forming method and actinic-ray- or radiation-sensitive resin composition | FUJIFILM CORPORATION (JP) | 2017-09-12 | — | — | US | disclosed |
| CN-103582696-B | Comprise the laundry care composition of dyestuff | THE PROCTER & GAMBLE CO. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | disclosed |
| EP-2297129-B1 | SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK SHARP & DOHME (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2013074388-A1 | SUBSTITUTED CYCLOPROPYL COMPOUNDS USEFUL AS GPR119 AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |
| EP-1574510-B1 | SUSBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-09 | — | — | EP | disclosed |
| US-7691785-B2 | Pyridine-3-ketone compound; plant growth controllers | SYNGENTA CROP PROTECTION, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-7691785-B2 | Pyridine-3-ketone compound; plant growth controllers | SYNGENTA CROP PROTECTION, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-7378375-B1 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378375-B1 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-27 | — | — | US | disclosed |
| US-20070151143-A1 | Stabilized biodiesel fuel compositions | CIBA SPECIALTY CHEMICALS CORP. | 2007-07-05 | — | — | US | disclosed |
| WO-2007021762-A2 | METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20060051478-A1 | Antioxidant for fats,oils and food | CIBA SPECIALTY CHEMICALS CORP. | 2006-03-09 | — | — | US | disclosed |
| EP-1571928-A2 | ANTIOXIDANT FOR FATS, OILS AND FOOD | Ciba SC Holding AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| CN-1178906-C | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ���Ͽع�����˾ | 2004-12-08 | — | — | CN | disclosed |
| WO-2004055141-A2 | ANTIOXIDANT FOR FATS, OILS AND FOOD | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-07-01 | — | — | WO | disclosed |
| CN-1261876-A | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ABBOTT LAB (US) | 2000-08-02 | — | — | CN | disclosed |
| US-4818749-A | Carboxyalkyl dipeptides and medical use thereof in treating hypertension and congestive heart failure | SCHERING CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |