Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | AGXT | P21549 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70291 | 0.97 | TSHR (0.74) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL53267 | 0.97 | TSHR (0.74) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL434644 | 0.88 | TSHR (0.61) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL5353833 | 0.88 | TSHR (0.61) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL71046 | 0.88 | TSHR (0.61) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL4675777 | 0.88 | TSHR (0.61) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL987625 | 0.88 | TSHR (0.61) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL5311581 | 0.88 | TSHR (1.00) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL27380 | 0.88 | TSHR (1.00) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL9575414 | 0.87 | TSHR (0.67) | TSHRIDO1AGXTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680201-A1 | COMPOSITIONS AND USES THEREOF FOR STABILIZATION OF BLOOD SAMPLE COMPONENTS | Streck LLC (US) | 2026-01-21 | — | — | EP | claimed |
| WO-2024192232-A9 | COMPOSITIONS AND USES THEREOF FOR STABILIZATION OF BLOOD SAMPLE COMPONENTS | STRECK LLC (US) | 2025-02-06 | — | — | WO | claimed |
| WO-2024192232-A1 | COMPOSITIONS AND USES THEREOF FOR STABILIZATION OF BLOOD SAMPLE COMPONENTS | STRECK LLC (US) | 2024-09-19 | — | — | WO | claimed |
| EP-4214255-A1 | REACTIVE COMPOUND FOR PRODUCING POLYURETHANE LAYERS HAVING THERMALLY ACTIVATABLE CATALYST SYSTEMS | Benecke-Kaliko AG (DE) | 2023-07-26 | — | — | EP | claimed |
| WO-2022057985-A1 | REACTIVE COMPOUND FOR PRODUCING POLYURETHANE LAYERS HAVING THERMALLY ACTIVATABLE CATALYST SYSTEMS | BENECKE-KALIKO AG (DE) | 2022-03-24 | — | — | WO | claimed |
| US-20200138787-A1 | COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-05-07 | — | — | US | claimed |
| US-10292967-B2 | Compositions comprising corneoscleral tissue cross-linking agents | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-05-21 | — | — | US | claimed |
| US-20190015388-A1 | COMPOSITIONS COMPRISING CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-01-17 | — | — | US | claimed |
| US-10105350-B2 | Cosmetic preservatives as therapeutic corneoscleral tissue cross-linking agents | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-10-23 | — | — | US | claimed |
| US-20160374992-A1 | COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-12-29 | — | — | US | claimed |
| EP-0848944-B1 | Sunscreen composition comprising long, branched chain alkyl benzoates or hydroxybenzoates | CPH INNOVATIONS CORP (US) | 2005-11-02 | — | — | EP | claimed |
| EP-1192938-A2 | Composition to enhance permeation of topical skin agents | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2002-04-03 | — | — | EP | claimed |
| US-6048516-A | DICYANODIPHENYLETHYLENE DERIVATIVE AND DIBENZOYLMETHANE; ULTRAVIOLET RADIATION ABSORBERS | ROCHE VITAMINS INC. (US) | 2000-04-11 | — | — | US | claimed |
| EP-0848944-A2 | Sunscreen composition comprising long, branched chain alkyl benzoates or hydroxybenzoates | The C.P. Hall Company (US) | 1998-06-24 | — | — | EP | claimed |
| EP-0365370-B1 | PHOTOSTABLE FILTERING COSMETIC COMPOSITION IN EMULSION FORM, CONTAINING A WATER SOLUBLE FILTER WITH A BROAD ABSORPTION BAND AND AT LEAST ONE FAT-SOLVING UV-A FILTER | L'OREAL (FR) | 1992-10-07 | — | — | EP | claimed |
| EP-0224938-B1 | INTERMEDIATES FOR THE PRODUCTION OF PODOPHYLLOTOXIN AND RELATED COMPOUNDS AND PROCESSES FOR THE PREPARATION AND USE THEREOF | Bristol-Myers Squibb Company (US) | 1992-06-17 | — | — | EP | claimed |
| US-5106996-A | Process for the preparation of podophyllotoxin | BRISTOL-MYERS COMPANY (US) | 1992-04-21 | — | — | US | claimed |
| EP-0365370-A1 | Photostable filtering cosmetic composition in emulsion form, containing a water soluble filter with a broad absorption band and at least one fat-solving UV-A filter | L'OREAL (FR) | 1990-04-25 | — | — | EP | claimed |
| EP-0224938-A2 | Intermediates for the production of podophyllotoxin and related compounds and processes for the preparation and use thereof | Bristol-Myers Squibb Company (US) | 1987-06-10 | — | — | EP | claimed |
| US-4029662-A | Method of making barbituric acid derivatives | BRISTOL-MYERS COMPANY (US) | 1977-06-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190015388-A1 | COMPOSITIONS COMPRISING CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS | SMCHD1, ALDH1A2, CRYAB | TSHR 3434/4885IDO1 3423/4885AGXT 1089/4885 |
| US-10105350-B2 | Cosmetic preservatives as therapeutic corneoscleral tissue cross-linking agents | COL1A1, COL14A1, COL2A1 | TSHR 2745/4885IDO1 3912/4885AGXT 2000/4885 |
| US-20200138787-A1 | COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS | ALDH1A2, FAAH, FAAH2 | TSHR 2194/4885IDO1 3460/4885AGXT 2253/4885 |
| US-10292967-B2 | Compositions comprising corneoscleral tissue cross-linking agents | SMCHD1, ALDH1A2, CRYAB | TSHR 3434/4885IDO1 3423/4885AGXT 1089/4885 |
| US-20160374992-A1 | COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS | COL1A1, COL14A1, COL2A1 | TSHR 2745/4885IDO1 3912/4885AGXT 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.