Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614813 | 0.90 | IDO1 (0.57) | IDO1AGXTTSHRNAAATAAR1 | |
| SCHEMBL5353833 | 0.88 | TSHR (0.61) | IDO1AGXTTSHRRAB9A | |
| SCHEMBL23906770 | 0.85 | TSHR (0.42) | IDO1AGXTTSHR | |
| Biphenyl SCHEMBL9577700 | 0.85 | ALDH1A1 (0.47) | IDO1AGXTTAAR1NPC1RAB9A | |
| SCHEMBL1337544 | 0.81 | AGXT (0.43) | IDO1AGXTTSHRNAAA | |
| SCHEMBL2781355 | 0.81 | TSHR (0.70) | IDO1AGXTTSHRNAAATAAR1 | |
| SCHEMBL13681248 | 0.81 | KEAP1 (0.36) | IDO1AGXTNAAATAAR1GSTP1 | |
| SCHEMBL10601291 | 0.79 | TSHR (0.75) | IDO1AGXTTSHRNAAATAAR1 | |
| SCHEMBL13813779 | 0.78 | IDO1 (0.53) | IDO1AGXTTSHRNAAATAAR1 | |
| Ether SCHEMBL9719783 | 0.78 | TP53 (0.54) | IDO1AGXTTSHRTAAR1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287549-A1 | TIME TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | FRESHPOINT HOLDINGS SA (CH) | 2011-11-24 | — | — | US | disclosed |
| US-20110287549-A1 | TIME TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | FRESHPOINT HOLDINGS SA (CH) | 2011-11-24 | — | — | US | disclosed |
| WO-2010092030-A1 | TIME-TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | FRESHPOINT HOLDINGS SA (CH) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287549-A1 | TIME TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | TPI1, TTI1, TST | IDO1 1091/4885AGXT 955/4885TSHR 1420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.