Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354290 | 1.00 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL5361782 | 0.92 | CEPT1 (0.48) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL5361789 | 0.92 | CEPT1 (0.48) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL7605004 | 0.91 | CEPT1 (0.48) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL6689662 | 0.87 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL19690361 | 0.86 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL29405696 | 0.86 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL231011 | 0.86 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL29924607 | 0.86 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL29924255 | 0.86 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531170-B1 | Ultraviolet blocking composition for protection of package or container contents | EASTMAN CHEM CO (US) | 2014-10-29 | — | — | EP | disclosed |
| US-7157547-B2 | Ultraviolet blocking composition for protection of package or container contents | EASTMAN CHEMICAL COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| EP-1325067-B1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEM CO (US) | 2006-09-06 | — | — | EP | disclosed |
| US-20050107574-A1 | Ultraviolet blocking composition for protection of package or container contents | EASTMAN CHEMICAL COMPANY | 2005-05-19 | — | — | US | disclosed |
| EP-1531170-A1 | Ultraviolet blocking composition for protection of package or container contents | EASTMAN CHEMICAL COMPANY (US) | 2005-05-18 | — | — | EP | disclosed |
| EP-1265876-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001064658-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2001-09-07 | — | — | WO | disclosed |
| US-6177574-B1 | REACTING 4,4'-BIS(BENZOXAZOL-2-YL)STILBENE WITH AN AMINOPHENOL AT A TEMPERATURE OF AT LEAST 200 DEGREES C IN THE PRESENCE OF AN INERT ORGANIC SOLVENT | EASTMAN CHEMICAL COMPANY | 2001-01-23 | — | — | US | disclosed |