SCHEMBL5361789

SCHEMBL5361789

Cc1cccc2oc(-c3ccc(C=Cc4ccc(-c5nc6c(C)cccc6o5)cc4)cc3)nc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CEPT1 Q9Y6K0 1/20 0.48
KDM4E B2RXH2 5/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
F2RL3 Q96RI0 4/20 0.41
AGPAT2 O15120 1/20 0.39
P2RY6 Q15077 1/20 0.39
HPGD P15428 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 3/20 0.39
UTRN P46939 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TP53 P04637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5361782 1.00 CEPT1 (0.48) CEPT1KDM4ECYP1A2CYP3A4MAPT
SCHEMBL7605004 0.96 CEPT1 (0.48) CEPT1KDM4ECYP1A2CYP3A4MAPT
SCHEMBL5354294 0.92 NPC1 (0.51) CEPT1KDM4EMAPTHPGDSMN1; SMN2
SCHEMBL5354290 0.92 NPC1 (0.51) CEPT1KDM4EMAPTHPGDSMN1; SMN2
SCHEMBL16231622 0.90 CEPT1 (0.54) CEPT1KDM4EF2RL3AGPAT2P2RY6
SCHEMBL11166470 0.88 CEPT1 (0.49) CEPT1KDM4EMAPTF2RL3AGPAT2
SCHEMBL13494491 0.85 SMN1; SMN2 (0.51) CEPT1KDM4ECYP1A2CYP3A4MAPT
SCHEMBL7298455 0.83 CEPT1 (0.52) CEPT1KDM4EF2RL3AGPAT2P2RY6
SCHEMBL9820032 0.83 UTRN (0.54) CEPT1F2RL3AGPAT2P2RY6SMN1; SMN2
SCHEMBL4584419 0.83 CEPT1 (0.49) CEPT1KDM4ECYP1A2F2RL3AGPAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1531170-B1 Ultraviolet blocking composition for protection of package or container contents EASTMAN CHEM CO (US) 2014-10-29 EP disclosed
US-7157547-B2 Ultraviolet blocking composition for protection of package or container contents EASTMAN CHEMICAL COMPANY (US) 2007-01-02 US disclosed
US-20050107574-A1 Ultraviolet blocking composition for protection of package or container contents EASTMAN CHEMICAL COMPANY 2005-05-19 US disclosed
EP-1531170-A1 Ultraviolet blocking composition for protection of package or container contents EASTMAN CHEMICAL COMPANY (US) 2005-05-18 EP disclosed
US-6177574-B1 REACTING 4,4'-BIS(BENZOXAZOL-2-YL)STILBENE WITH AN AMINOPHENOL AT A TEMPERATURE OF AT LEAST 200 DEGREES C IN THE PRESENCE OF AN INERT ORGANIC SOLVENT EASTMAN CHEMICAL COMPANY 2001-01-23 US disclosed