SCHEMBL5354313

SCHEMBL5354313

COc1cc(Bc2cc(C)c(F)cc2F)c(F)cc1F

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 3/20 0.37
RAB9A P51151 2/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
EGFR P00533 1/20 0.32
HTR1A P08908 1/20 0.31
KDM1A O60341 2/20 0.30
ILK Q13418 1/20 0.30
MAPT P10636 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
NCOA1 Q15788 1/20 0.30
NCOA3 Q9Y6Q9 1/20 0.30
NPC1 O15118 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5357655 0.90 LMNA (0.37) TUBB1RAB9ALMNAMAPK1HTT
SCHEMBL5347763 0.84 GPR3 (0.35)
SCHEMBL16200092 0.82 TUBB1 (0.44) TUBB1RAB9ALMNAMAPK1HTT
SCHEMBL5346819 0.80 TUBB1 (0.33) TUBB1
SCHEMBL5351574 0.78 TUBB1 (0.33) TUBB1
SCHEMBL5352021 0.78 TUBB1 (0.34) TUBB1
SCHEMBL5352417 0.78
SCHEMBL6063350 0.78 TUBB1 (0.39) TUBB1RAB9ALMNAMAPK1HTT
SCHEMBL12216028 0.78 TUBB1 (0.44) TUBB1RAB9ALMNAMAPK1HTT
SCHEMBL5357118 0.77 TUBB1 (0.34) TUBB1RAB9ALMNAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217676-B2 Hydrophobization and silica for supported catalyst EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-05-15 US disclosed
US-20060264320-A1 Hydrophobization and silica for supported catalyst RODRIGUEZ GEORGE 2006-11-23 US disclosed
EP-1704171-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST ExxonMobil Chemical Patents Inc. (US) 2006-09-27 EP disclosed
WO-2005075526-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-08-18 WO disclosed
US-20050159299-A1 Hydrophobization and silica for supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed