Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | ACHE | P22303 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | NCF1 | P14598 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803647 | 0.98 | HTR3A (0.73) | HTR3AKDM4EGAAL3MBTL1ACHE | |
| SCHEMBL27866891 | 0.86 | NCF1 (0.69) | HTR3AKDM4EGAAL3MBTL1ACHE | |
| SCHEMBL5910851 | 0.86 | HTR3A (1.00) | HTR3AKDM4EALDH1A1NCF1USP2 | |
| SCHEMBL14692030 | 0.83 | HTR3A (0.61) | HTR3AKDM4EGAAL3MBTL1ACHE | |
| SCHEMBL5355974 | 0.81 | HTR3A (0.51) | HTR3AKDM4EGAAL3MBTL1ACHE | |
| SCHEMBL28403687 | 0.80 | KDM4E (0.67) | HTR3AKDM4EGAAL3MBTL1ACHE | |
| SCHEMBL8249581 | 0.80 | KDM4E (0.67) | HTR3AKDM4EGAAL3MBTL1ACHE | |
| SCHEMBL26723750 | 0.80 | KDM4E (1.00) | HTR3AKDM4EGAAL3MBTL1ACHE | |
| SCHEMBL29351521 | 0.79 | KDM4E (1.00) | HTR3AKDM4EGAAL3MBTL1ACHE | |
| SCHEMBL14975993 | 0.79 | KDM4E (1.00) | HTR3AKDM4EGAAL3MBTL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189714-B2 | N-type calcium channel antagonists for the treatment of pain | ASTRAZENECA AB (SE) | 2007-03-13 | — | — | US | disclosed |