Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.65 |
| ▸ | ABAT | P80404 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | F3 | P13726 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361345 | 0.81 | ALDH5A1 (0.62) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| SCHEMBL2394894 | 0.79 | ALDH5A1 (1.00) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| Water SCHEMBL9413887 | 0.79 | ALDH5A1 (0.60) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| SCHEMBL23659100 | 0.79 | ALDH5A1 (0.60) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| SCHEMBL7827411 | 0.79 | ALDH5A1 (0.60) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| SCHEMBL15219085 | 0.78 | APP (0.59) | ALDH5A1ABATMAPTALDH1A1F3 | |
| SCHEMBL28515948 | 0.77 | MAPT (0.59) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| SCHEMBL8903743 | 0.76 | MAPT (0.55) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| SCHEMBL4421107 | 0.75 | ALDH5A1 (0.56) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| SCHEMBL10917423 | 0.75 | MAPT (1.00) | ALDH5A1ABATMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208551-B2 | Polyaryleneetherketone phosphine oxide compositions incorporating cycloaliphatic units for use as polymeric binders in thermal control coatings and method for synthesizing same | UNIVERSITY OF DAYTON (US) | 2007-04-24 | — | — | US | disclosed |
| US-20050043449-A1 | Polyaryleneetherketone phosphine oxide compositions incorporating cycloaliphatic units for use as polymeric binders in thermal control coatings and method for synthesizing same | UNIVERSITY OF DAYTON | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043449-A1 | Polyaryleneetherketone phosphine oxide compositions incorporating cycloaliphatic units for use as polymeric binders in thermal control coatings and method for synthesizing same | PNKP, PHOSPHO1, KTN1 | ALDH5A1 4479/4885ABAT 3072/4885MAPT 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.