Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077425 | 0.87 | APP (0.49) | APPESR1ESR2LMNAMAPT | |
| Anemarchalconyn SCHEMBL775177 | 0.84 | APP (0.82) | APPESR1ESR2MAPTALDH1A1 | |
| SCHEMBL10428831 | 0.83 | CA1 (0.53) | APPESR1ESR2LMNAMAPT | |
| SCHEMBL8903743 | 0.81 | MAPT (0.55) | APPESR1ESR2LMNAMAPT | |
| SCHEMBL21180312 | 0.80 | HSD17B3 (0.52) | APPESR1ESR2LMNAMAPT | |
| SCHEMBL12060209 | 0.79 | ESR1 (0.52) | APPESR1ESR2LMNAMAPT | |
| SCHEMBL10363774 | 0.79 | MAPT (0.52) | APPESR1ESR2LMNAMAPT | |
| SCHEMBL13077427 | 0.79 | VCP (0.71) | APPLMNAMAPTHTTCA1 | |
| SCHEMBL5354484 | 0.78 | ALDH5A1 (0.65) | ESR1ESR2LMNAMAPTPKM | |
| Paraben SCHEMBL21061691 | 0.74 | CA2 (0.94) | ESR1ESR2LMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391666-B1 | CROSS-LINKABLE AROMATIC POLYCARBONATE | NEXAM CHEMICAL AB (SE) | 2013-08-28 | — | — | EP | disclosed |