SCHEMBL5355063

SCHEMBL5355063

[CH2]C(=C(C)C)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.44
CES1 P23141 3/20 0.44
TSHR P16473 3/20 0.42
MAPT P10636 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
PARP1 P09874 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
ESR1 P03372 1/20 0.38
AKT1 P31749 1/20 0.37
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7542933 0.82 TDP1 (0.50) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL7542937 0.82 TDP1 (0.50) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL10860577 0.81 ESR1 (0.46) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL688558 0.79
SCHEMBL18884554 0.77 CES2 (0.48) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL3847946 0.74 TSHR (0.43) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL3684165 0.72 ESR1 (0.48) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL3684167 0.72 ESR1 (0.48) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL3854316 0.72 ESR1 (0.48) CES2CES1TSHRMAPTL3MBTL1
Hydrogen Peroxide SCHEMBL7249472 0.71 CES2 (0.48) CES2CES1TSHRMAPTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3589671-B1 MULTI-COMPONENT ADHESIVE SYSTEM ARKEMA FRANCE (FR) 2023-12-13 EP disclosed
WO-2018160535-A1 MULTI-COMPONENT ADHESIVE SYSTEM HERCULES LLC (US) 2018-09-07 WO disclosed
US-7250455-B2 Physical entrapment phase (e.g. organoclay) to physically prevent the agglomeration of the sub-micron \"use\" particles such as polytetrafluoroethylene (PTFE) latex which is dispersable in the target medium and imparts desirable properties while using lower amount of compatibilizing agents SHAMROCK TECHNOLOGIES, INC. (US) 2007-07-31 US disclosed
CN-1313586-C Fabric care compositions UNILEVER NV (NL) 2007-05-02 CN disclosed
US-7189769-B2 Imparting desirable properties to a target medium while using less compatibilizing agents by using a physical entrapment phase (e.g. organoclay) dispersible in said medium to physically prevent the agglomeration of the sub-micron particles such as polytetrafluoroethylene (PTFE) latex SHAMROCK TECHNOLOGIES, INC. (US) 2007-03-13 US disclosed
EP-1534779-A4 PHYSICAL METHODS OF DISPERSING CHARACTERISTICS USE PARTICLES AND COMPOSITIONS THEREOF SHAMROCK TECH INC (US) 2006-03-15 EP disclosed
EP-1545735-A4 METHOD FOR INCORPORATING CATIONIC MOLECULES INTO A SUBSTRATE FOR INCREASING DISPERSIBILITY OF CATIONIC MOLECULES CODY CHARLES A (US) 2005-09-28 EP disclosed
EP-1545735-A2 METHOD FOR INCORPORATING CATIONIC MOLECULES INTO A SUBSTRATE FOR INCREASING DISPERSIBILITY OF CATIONIC MOLECULES Shamrock Technologies, Inc. (US) 2005-06-29 EP disclosed
EP-1545756-A2 METHOD FOR INCORPORATING ANIONIC MOLECULES INTO A SUBSTRATE FOR INCREASING DISPERSIBILITY OF ANIONIC MOLECULES Shamrock Technologies, Inc. (US) 2005-06-29 EP disclosed
US-6911488-B2 Characteristic use particles entrapped within a physical entrapment phase that is dispersible in the target medium to physically prevent the agglomeration or self-association SHAMROCK TECHNOLOGIES, INC. (US) 2005-06-28 US disclosed
EP-0265101-A2 Biocidal thickening additive for an organic composition RHEOX INTERNATIONAL, INC. (US) 1988-04-27 EP disclosed
US-4695402-A Organophilic clay gellants and process for preparation NL CHEMICALS, INC. (US) 1987-09-22 US disclosed
US-4664820-A Preactivated organophilic clay gellant lubricating grease thickened with preactivated organophilic clay gellant and process for preparing preactivated organophilic clay gellants NL INDUSTRIES, INC. (US) 1987-05-12 US disclosed
US-4659571-A SELF-SUPPORTING STICK WITH ACCEPTABLE PAYOUT; ANTIPERSPIRANTS; DEODORANTS NL INDUSTRIES, INC. (US) 1987-04-21 US disclosed
EP-0203681-A1 Compressed powder formulation containing organophilic clay and a process for making the formulation RHEOX INTERNATIONAL, INC. (US) 1986-12-03 EP disclosed
US-4620994-A Color plus clear coating system utilizing organo-modified clay PPG INDUSTRIES, INC. (US) 1986-11-04 US disclosed
US-4620993-A Color plus clear coating system utilizing organo-modified clay in combination with organic polymer microparticles PPG INDUSTRIES, INC. (US) 1986-11-04 US disclosed
US-4558075-A CROSSLINKABLE RESIN BINDER, SOLVENT SYSTEM, AND CLAY DISPERSED THEREIN PPG INDUSTRIES, INC. (US) 1985-12-10 US disclosed
US-4434076-A QUATERNARY AMMONIUM-SMECTITE COMPLEXES NL INDUSTRIES, INC. (US) 1984-02-28 US disclosed
US-4391637-A Rheological additive for non-aqueous fluid systems NL INDUSTRIES, INC. (US) 1983-07-05 US disclosed