Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.47 |
| ▸ | CES2 | O00748 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542937 | 1.00 | TDP1 (0.50) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL3847946 | 0.84 | TSHR (0.43) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL5355063 | 0.82 | CES2 (0.44) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL10860577 | 0.80 | ESR1 (0.46) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL4133635 | 0.79 | — | — | |
| SCHEMBL147615 | 0.79 | CES2 (0.56) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL6046218 | 0.77 | TDP1 (0.56) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL717977 | 0.77 | TDP1 (0.56) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL6401253 | 0.77 | TDP1 (0.56) | TDP1TSHRCYP3A4MAPTBLM | |
| SCHEMBL688558 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104429-B1 | ANSA GROUP-4-METAL BIS (.MU.-SUBSTITUTED) ALUMINUM COMPLEXES | DOW CHEMICAL CO (US) | 2002-05-08 | — | — | EP | disclosed |
| EP-1104429-A1 | ANSA GROUP-4-METAL BIS (.MU.-SUBSTITUTED) ALUMINUM COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-06-06 | — | — | EP | disclosed |
| US-6140521-A | CONTACTING A CHARGE-NEUTRAL GROUP IV METAL COORDINATION COMPLEX HAVING AT LEAST TWO LEWIS BASIC GROUPS WITH A CHARGE-NEUTRAL ALUMINUM COORDINATION COMPLEXES HAVING LEWIS ACIDIC ALUMINUM ATOMS; OLEFIN POLYMERIZATION CATALYST | THE DOW CHEMICAL COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| WO-2000009523-A1 | ANSA-GROUP-4-METAL BIS (.MU.-SUBSTITUTED) ALUMINUM COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-02-24 | — | — | WO | disclosed |